Evidence map›Paper›PMID 36310657›Full record

ArticleReproductive medicine and biology

Shallow artificial networks with morphokinetic time-lapse parameters coupled to ART data allow to predict live birth.

Mehdi Benchaib, Elsa Labrune, Sandrine Giscard d'Estaing, Bruno Salle, Jacqueline Lornage

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. A review of artificial intelligence applications in in vitro fertilization.Journal of assisted reproduction and genetics · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehdi BenchaibHospices Civil de Lyon, HFME, Médecine de la Reproduction & Préservation de la Fertilité Féminine Bron cedex France.ORCID https://orcid.org/0000-0001-5250-6036
Elsa LabruneHospices Civil de Lyon, HFME, Médecine de la Reproduction & Préservation de la Fertilité Féminine Bron cedex France.
Sandrine Giscard d'EstaingHospices Civil de Lyon, HFME, Médecine de la Reproduction & Préservation de la Fertilité Féminine Bron cedex France.
Bruno SalleHospices Civil de Lyon, HFME, Médecine de la Reproduction & Préservation de la Fertilité Féminine Bron cedex France.
Jacqueline LornageHospices Civil de Lyon, HFME, Médecine de la Reproduction & Préservation de la Fertilité Féminine Bron cedex France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this work was to construct shallow neural networks (SNN) using time-lapse technology (TLT) from morphokinetic parameters coupled to assisted reproductive technology (ART) parameters in order to assist the choice of embryo(s) to be transferred with the highest probability of achieving a live birth (LB). Methods: A retrospective observational single-center study was performed, 654 cycles were included. Three SNN: multilayers perceptron (MLP), simple recurrent neuronal network (simple RNN) and long short term memory RNN (LSTM-RNN) were trained with K-fold cross-validation to avoid sampling bias. The predictive power of SNNs was measured using performance scores as AUC (area under curve), accuracy, precision, Recall and F1 score Results: In the training data group, MLP and simple RNN provide the best performance scores; however, all AUCs were above 0.8. In the validating data group, all networks were equivalent with no performance scores difference and all AUC values were above 0.8. Conclusion: Coupling morphokinetic parameters with ART parameters allows to SNNs to predict the probability of LB, and all SNNs seems to be efficient according to the performance scores. An automatic time recognition system coupled to one of these SNNs could allow a complete automation to choose the blastocyst(s) to be transferred.

Indexed as

artificial intelligenceblastocystembryo selectiontime lapse

Identifiers

PMID36310657
PMCPMC9601773

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.