ArticleGlobal pediatric health2022
Red Blood Cell Alloimmunization in Pediatric group with Beta Thalassemia: A Five-Year Experience.
Article in Global pediatric health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Incidence and determinants of red cell alloimmunization and autoimmunization in paediatric thalassaemia: A North Indian cohort study.Vox sanguinis · 2026Observational
- Prevalence of Alloimmunization Events in Thalassemia Patients With Repeated Transfusions in the Rhesus Blood Group System: A Systematic Review and Meta Analysis.Journal of clinical medicine research · 2025Article
- Characterization of pediatric transfusion-dependent thalassemia patients in a large academic center.Journal of clinical laboratory analysis · 2023Article
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Authors and funding
6 authors.
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Abstract
Beta-thalassemia is one of the most frequently occurring hematological disorders in [Removed for blinded peer-review]. Regular blood transfusion is required in almost all cases for management. However, this is associated with significant major complications like red blood cell (RBC) alloimmunization. This retrospective cross-sectional is conducted to evaluate the RBC alloimmunization frequency in children with beta-thalassemia aged between 6 months and 16 years in [Removed for blinded peer-review]. Antibody screening was performed using the Dia clon3 cell antigen panel. If the screening came back positive, a detailed panel was created for the identification of specific antibody. In our sample, the frequency of RBC alloimmunization was found in 22 (26.19%) patients. Of these 22 patients, the Rhesus system was found in most patients 17 (77.3%), followed by Kell 5 (22.7%). RBC alloimmunization was significantly associated with a family history of a blood disorder and splenectomy.
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