Evidence map›Paper›PMID 36310400›Full record

ArticleArtificial organs2023

Additive effectiveness of acrylonitrile-co-methallyl sulfonate surface-treated membranes in the treatment of pneumonia: A propensity score-matched retrospective cohort study.

Kentaro Hayashi, Yusuke Sasabuchi, Hiroki Matsui, Mikio Nakajima, Hiroyuki Ohbe, Kiyohide Fushimi, Kazuyuki Ono, Hideo Yasunaga

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Artificial organs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kentaro HayashiDepartment of Emergency and Critical Care Medicine, Dokkyo Medical University, Tochigi, Japan.ORCID https://orcid.org/0000-0003-0775-9821
Yusuke SasabuchiData Science Center, Jichi Medical University, Tochigi, Japan.
Hiroki MatsuiDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Mikio NakajimaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Hiroyuki OhbeDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Tokyo Medical and Dental University Graduate School of Medicine, Tokyo, Japan.
Kazuyuki OnoDepartment of Emergency and Critical Care Medicine, Dokkyo Medical University, Tochigi, Japan.
Hideo YasunagaDepartment of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
University of Tokyo Health Sciences · JPJichi Medical University · JPDokkyo Medical University · JPTokyo Medical and Dental University · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology, Japan 17H04141Ministry of Health, Labour and Welfare, Japan 19AA2007Ministry of Health, Labour and Welfare, Japan H30-Policy-Designated-004
6 · The paper itself

Abstract

backgroundThe acrylonitrile-co-methallyl sulfonate surface-treated (AN69ST) membrane has cytokine adsorption capacity and is used for treating sepsis. This study aimed to compare the effects of continuous renal replacement therapy (CRRT) using the AN69ST membrane with those of CRRT using other membranes for patients with pneumonia-associated sepsis.

methodsThis retrospective, propensity score-matched, cohort study was based on a nationwide Japanese inpatient database. We included data from adults hospitalized with a primary diagnosis of pneumonia, who received CRRT using either the AN69ST membrane or another membrane within 2 days of admission, and who were discharged from the hospitals between September 2014, and March 2017. Propensity score matching was used to compare in-hospital mortality between the two groups.

resultsEligible patients (N = 2393) were categorized into an AN69ST group (N = 631) and a non-AN69ST group (N = 1762). The overall in-hospital mortality rate was 38.9%. Among the 545 propensity-matched patient pairs, the in-hospital mortality rate was significantly lower in the AN69ST group than in the non-AN69ST group (35.8 vs. 41.8%, p = 0.046).

conclusionsAmong patients with pneumonia-associated sepsis treated with CRRT, CRRT with the AN69ST membrane was associated with a significantly lower in-hospital mortality than CRRT with standard membranes.

Indexed as

AcrylonitrileAcute Kidney InjuryPneumoniaSepsisAdultAlkanesulfonatesCohort StudiesHumansPropensity ScoreRenal Replacement TherapyRetrospective StudiesAcrylonitrileAlkanesulfonatesmethallyl sulfonateacrylonitrile-co-methallyl sulfonate membranecontinuous renal replacement therapycytokine adsorption therapypneumoniasepsis

Identifiers

PMID36310400
PMCPMC10099711
OpenAlexW4307770960

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.