Evidence map›Paper›PMID 36310302›Full record

SynthesisInternal and emergency medicine2023

Point-of-care ultrasound improves clinical outcomes in patients with acute onset dyspnea: a systematic review and meta-analysis.

Gergő Vilmos Szabó, Csenge Szigetváry, László Szabó, Fanni Dembrovszky, Máté Rottler, Klemetina Ocskay, Stefanie Madzsar, Péter Hegyi, Zsolt Molnár

Full text readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Internal and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Sample Size of Trials Investigating the Impact of Point-of-Care Ultrasound-Guided Strategies on Patient Outcomes: A Systematic Review.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gergő Vilmos SzabóCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Csenge SzigetváryCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
László SzabóCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Fanni DembrovszkyCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Máté RottlerInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.
Klemetina OcskayCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Stefanie MadzsarCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary.
Zsolt MolnárCentre for Translational Medicine, Semmelweis University, Üllői út 26, Budapest, 1085, Hungary. zsoltmolna@gmail.com.

Funding

Hungarian National Research, Development and Innovation Office Grant No: K 138816
6 · The paper itself

Abstract

The early, appropriate management of acute onset dyspnea is important but often challenging. The aim of this study was to investigate the effects of the use of Point-of-Care Ultrasound (PoCUS) versus conventional management on clinical outcomes in patients with acute onset dyspnea. The Cochrane Library, MEDLINE, EMBASE and reference lists were searched to identify eligible trials (inception to October 14, 2021). There were no language restrictions. Randomized controlled trials (RCTs), and prospective and retrospective cohort studies that compared PoCUS with conventional diagnostic modalities (controls) in patients with acute onset dyspnea were included. Two independent reviewers extracted data and assessed the risk of bias. Disagreements were resolved by consensus. The primary study outcomes were time to diagnosis, time to treatment, and length of stay (LOS). Secondary outcomes included rate of appropriate treatment, 30-day re-admission rate, and mortality. We included eight RCTs and six observational studies with a total of 5393 participants. Heterogeneity across studies was variable (from low to considerable), with overall low or moderate study quality and low or moderate risk of bias (except one article with serious risk of bias). Time to diagnosis (mean difference [MD], - 63 min; 95% CI, - 115 to - 11 min] and time to treatment (MD, - 27 min; 95% CI - 43 to - 11 min) were significantly shorter in the PoCUS group. In-hospital LOS showed no differences between the two groups, but LOS in the Intensive Care Unit (MD, - 1.27 days; - 1.94 to - 0.61 days) was significantly shorter in the PoCUS group. Patients in the PoCUS group showed significantly higher odds of receiving appropriate therapy compared to controls (odds ratio [OR], 2.31; 95% CI, 1.61-3.32), but there was no significant effect on 30-day re-admission rate and in-hospital or 30-day mortality. Our results indicate that PoCUS use contributes to early diagnosis and better outcomes compared to conventional methods in patients admitted with acute onset dyspnea.

Indexed as

HospitalizationPoint-of-Care SystemsDyspneaHumansIntensive Care UnitsLength of StayAcute-onset dyspneaClinical outcomesPoint-of-care ultrasound

Identifiers

PMID36310302
PMCPMC10017566

What OpenQuestion holds

Textfull text, public
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measurements read37
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.