ArticleCardiovascular diabetology2022
Diabetes mellitus duration and mortality in patients hospitalized with acute myocardial infarction.
Article in Cardiovascular diabetology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- β-blocker and clinical outcomes in patients after myocardial infarction: a systematic review and meta-analysis.European journal of clinical pharmacology · 2025Pooled it
- Platelets mediate fibrin-induced thromboinflammation and NETosis through a GPVI-polyphosphate-FXIIa procoagulant axis.Blood vessels, thrombosis & hemostasis · 2026Article
- Emerging Prognostic Risk Factors in Acute Coronary Syndromes: Beyond Traditional Risk Assessment.Journal of clinical medicine · 2026Review
- Advanced glycation end-products exacerbate myocardial ischemia/reperfusion injury by promoting mitochondrial oxidative damage and PANoptosis in diabetes mellitus.Redox biology · 2026Article
- Predicting long-term major adverse cardiac events after percutaneous coronary intervention in individuals with acute coronary syndrome and nonvalvular atrial fibrillation: a machine learning study.BMC cardiovascular disorders · 2026Article
- Sweet relief: exploring mechanisms and therapeutic approaches of sodium-glucose cotransporter-2 inhibitors in cardiovascular-kidney metabolic syndrome.Cardiovascular diabetology · 2026Review
- Relationship between hemoglobin glycation index and all-cause mortality in patients with acute myocardial infarction: based on MIMIC-IV database.Diabetology & metabolic syndrome · 2025Article
- Inflammatory markers guide early risk stratification and prognosis in elderly patients with acute myocardial infarction.Scientific reports · 2025Article
- Deep learning-based prognosis of major adverse cardiac events in patients with acute myocardial infarction: a retrospective observational study in the Republic of Korea.Osong public health and research perspectives · 2025Article
- Glycemic Comparison Index (GCI): a retrospective analysis of its prognostic value in ICU patients with AMI and diabetes.BMC endocrine disorders · 2025Article
- Independent influence of type 2 diabetes on reduced cardiopulmonary fitness in patients after percutaneous coronary intervention: a cross-sectional study.Scientific reports · 2025Article
- Machine learning approaches for risk prediction after percutaneous coronary intervention: a systematic review and meta-analysis.European heart journal. Digital health · 2025Article
- Plasma tissue plasminogen activator-inhibitor complex levels in acute myocardial infarction patients: an observational study.BMC cardiovascular disorders · 2024Observational
- Prescription Fills Among Patients With Type 2 Diabetes After Hospitalization for Acute Coronary Syndrome.JAMA network open · 2024Article
- Short- and long-term mortality in patients with type 2 diabetes after myocardial infarction- a nationwide registry study.Cardiovascular diabetology · 2024Observational
- Association of Iron Therapy with Mortality in Patients with Acute Myocardial Infarction and Iron Deficiency.Cardiovascular toxicology · 2024Article
- Emerging opportunities to target inflammation: myocardial infarction and type 2 diabetes.Cardiovascular research · 2024Review
- In-Hospital Mortality in Patients With Acute Myocardial Infarction: A Literature Overview.Cureus · 2024Review
- The effect of prognostic nutritional index on diabetic patients with myocardial infarction.Diabetology & metabolic syndrome · 2024Article
- Trends in Survival After First Myocardial Infarction in People With Diabetes.Journal of the American Heart Association · 2024Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetes mellitus (DM) is associated with an increased mortality risk in patients hospitalized with acute myocardial infarction (AMI); however, no studies have investigated the impact of the duration of DM on in-hospital mortality. In this study, we evaluated in-hospital mortality in AMI patients according to DM status and its duration.
methodsUsing health administrative databases of Lombardy, DM patients≥50 years hospitalized with AMI from 2010 to 2019 were included in the analysis and were stratified according to the duration of DM: <5, 5-10, and > 10 years. The primary endpoint was mortality during AMI hospitalization and the secondary endpoint was 1-year mortality in comparison with No-DM patients. Logistic and Cox regressions analyses were used to estimate odds ratios (ORs, CI 95%) and hazard ratios (HRs, CI 95%) for the outcomes, according to DM status and duration and AMI type (STEMI and NSTEMI).
resultsOur study cohort comprised 29,566 and 109,247 DM and No-DM patients, respectively. Adjusted ORs and HRs showed a significantly higher risk of in-hospital mortality (OR 1.50, 95% CI 1.43-1.58) and 1-year mortality (HR 1.51, 95% CI 1.46-1.55) in DM patients in comparison with those without. These risks increased progressively with the duration of DM, with the highest risk observed in patients with DM duration ≥ 10 years (OR 1.59, 95% CI 1.50-1.69 for in-hospital mortality and HR 1.59, 95% CI 1.53-1.64 for 1-year mortality). These findings were similar in STEMI and in NSTEMI patients.
conclusionsOur study demonstrates that the duration of DM parallels mortality risk in patients hospitalized with AMI, highlighting that DM duration should be considered as an important early prognostic risk factor in patients with AMI.
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