Evidence map›Paper›PMID 36309636›Full record

ArticleEuropean journal of hybrid imaging2022

Reproducibility of lung cancer radiomics features extracted from data-driven respiratory gating and free-breathing flow imaging in [

Daphné Faist, Mario Jreige, Valentin Oreiller, Marie Nicod Lalonde, Niklaus Schaefer, Adrien Depeursinge, John O Prior

Open access · goldAbstract read
In one paragraph

Article in European journal of hybrid imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Characterization of canine metastatic pulmonary nodules onThe Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact of respiratory motion onJournal of applied clinical medical physics · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daphné FaistDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-0994-4329
Mario JreigeDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-3918-150X
Valentin OreillerInstitute of Information Systems, University of Applied Sciences Western Switzerland, (HES-SO), Rue du Technopôle 3, CH-3960, Sierre, Switzerland.ORCID https://orcid.org/0000-0002-7794-6916
Marie Nicod LalondeDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-4886-0611
Niklaus SchaeferDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-9732-7696
Adrien DepeursingeDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-2362-0304
John O PriorDepartment of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Rue du Bugnon 46, CH-1011, Lausanne, Switzerland. john.prior@chuv.ch.ORCID https://orcid.org/0000-0003-1429-1374
University of Lausanne · CHHES-SO University of Applied Sciences and Arts Western Switzerland · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuality and reproducibility of radiomics studies are essential requirements for the standardisation of radiomics models. As recent data-driven respiratory gating (DDG) [

methodsTwenty four lung nodules from 20 patients were delineated. Radiomics features were derived on FB flow PET/CT and on the corresponding DDG reconstruction using the QuantImage v2 platform. Lin's concordance factor (C

resultsIn total 141 features were computed on each concordance analysis, 10 of which were non-reproducible on all pulmonary lesions. Those were first-order features from Laplacian of Gaussian (LoG)-filtered images (sigma = 1 mm): Energy, Kurtosis, Minimum, Range, Root Mean Squared, Skewness and Variance; Texture features from Gray Level Cooccurence Matrix (GLCM): Cluster Prominence and Difference Variance; First-order Standardised Uptake Value (SUV) feature: Kurtosis. Pulmonary lesions located in the superior lobes had only stable radiomics features, the ones from the lower parts had 25 non-reproducible radiomics features. Pulmonary lesions with a greater size (defined as long axis length > median) showed a higher reproducibility (9 non-reproducible features) than smaller ones (20 non-reproducible features).

conclusionCalculated on all pulmonary lesions, 131 out of 141 radiomics features can be used interchangeably between DDG and FB PET/CT acquisitions. Radiomics features derived from pulmonary lesions located inferior to the superior lobes are subject to greater variability as well as pulmonary lesions of smaller size.

Indexed as

[18F]-FDGData-driven gatingData-driven respiratory gatingLung PET/CTPET/CTPulmonary noduleRadiomics featuresReproducibilityRespiratory gating

Identifiers

PMID36309636
PMCPMC9617997
OpenAlexW4307811141

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.