Evidence map›Paper›PMID 36309564›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Effectiveness of a care bundle for primary prevention of intraventricular hemorrhage in high-risk neonates: a Bayesian analysis.

Benjamin J S Al-Haddad, Brittany Bergam, Alicia Johnson, Sarah Kolnik, Taylor Thompson, Krystle M Perez, Jacob Kennedy, Daniel A Enquobahrie, Sandra E Juul, Kendell German

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Impact of Early Hemodynamic Screening on Extremely Preterm Outcomes in a High-Performance Center.American journal of respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Benjamin J S Al-HaddadUniversity of Minnesota Department of Pediatrics, Division of Neonatology, Minneapolis, MN, USA. haddad@umn.edu.ORCID http://orcid.org/0000-0003-1398-9527
Brittany BergamUniversity of Washington School of Medicine, Seattle, WA, USA.
Alicia JohnsonMacalester College, Mathematics, Statistics, and Computer Science, St. Paul, MN, USA.
Sarah KolnikUniversity of Washington Department of Pediatrics, Division of Neonatology, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1397-8430
Taylor ThompsonUniversity of Washington School of Medicine, Seattle, WA, USA.
Krystle M PerezUniversity of Washington Department of Pediatrics, Division of Neonatology, Seattle, WA, USA.
Jacob KennedyUniversity of Washington School of Medicine, Seattle, WA, USA.
Daniel A EnquobahrieDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA.
Sandra E JuulUniversity of Washington Department of Pediatrics, Division of Neonatology, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6861-6229
Kendell GermanUniversity of Washington Department of Pediatrics, Division of Neonatology, Seattle, WA, USA.
University of Washington · USMacalester College · USUniversity of Minnesota · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008244 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHIMIZU, YOJI · 1988 to 2024
$13.6M
NIGMS NIH HHS T32 GM008244
6 · The paper itself

Abstract

objectiveTo determine whether an intraventricular hemorrhage (IVH) prevention bundle featuring midline-elevated positioning reduced IVH among high-risk infants. STUDY

designIn a retrospective study design, we compared outcomes of infants <1250 grams birth weight or <30 weeks gestation before (N = 205) and after (N = 360) implementation of an IVH prevention bundle, using Bayesian and frequentist logistic regression to determine whether the intervention decreased any grade IVH.

resultsIn both the Bayesian and frequentist analyses, there was no difference in odds of any grade IVH before and after the implementation of the prevention bundle (OR 0.993; 95% Credible Interval 0.751-1.323 and OR 1.23; 95% Confidence Interval 0.818-1.864 respectively). Bias analyses suggested that these results were robust to bias from potential deaths attributable to IVH.

conclusionIn this retrospective analysis, we found no evidence for a protective effect of an IVH prevention bundle on IVH incidence among high-risk neonates at a level IV NICU.

Indexed as

Infant, Premature, DiseasesPatient Care BundlesBayes TheoremCerebral HemorrhageGestational AgeHumansInfantInfant, NewbornInfant, PrematurePrimary PreventionRetrospective Studies

Identifiers

PMID36309564
OpenAlexW4307658334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.