Evidence map›Paper›PMID 36309405›Full record

ArticleIn vivo (Athens, Greece)

Effect of Underwater Exercise on Salivary Metabolites of Older Persons With Disability.

Nobuaki Tamura, Kazu Mizuno, Ryuichiro Suzuki, Masahiro Sugimoto, Ayame Enomoto, Sana Ota, Miku Kaneko, Hiroshi Sakagami, Hiroshi Takeshima

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nobuaki TamuraDivision of Geriatric Dentistry, Meikai University School of Dentistry, Saitama, Japan; nobutamura@dent.meikai.ac.jp.
Kazu MizunoJP Swimming Club, Josai University, Saitama, Japan.
Ryuichiro SuzukiDepartment of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, Saitama, Japan.
Masahiro SugimotoInstitute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Ayame EnomotoInstitute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Sana OtaInstitute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Miku KanekoInstitute for Advanced Biosciences, Keio University, Tsuruoka, Japan.
Hiroshi SakagamiMeikai University Research Institute of Odontology (M-RIO), Saitama, Japan sakagami@dent.meikai.ac.jp.
Hiroshi TakeshimaDivision of Geriatric Dentistry, Meikai University School of Dentistry, Saitama, Japan.
Keio University · JPMeikai University · JPJosai University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimUnderwater exercise is aimed at preventing aging, maintaining, and improving motor function, and improving physical function. However, its rehabilitation effects have not been well evaluated. In order to gain insight into the molecular basis of its rehabilitation effects, possible changes in the salivary metabolites of four older persons with disability (mean age: 72.5 years) during underwater exercise were investigated. MATERIALS AND

methodsHalitosis was measured by Breathtron; salivary bacterial number by bacterial counter; amino acids by amino acid analyzer; 8-oxoguanine by ELISA; and intracellular metabolites by capillary electrophoresis, time-of-flight mass spectrometry, liquid chromatography, and triode quadrupole mass spectrometry.

resultsUnderwater exercise induced apparent declines in two major salivary amino acids (glycine and proline) and bacterial numbers in the cheek mucosa and salivary, without apparent changes in the halitosis and urine 8-oxoguanine concentration. Older subjects showed higher concentrations of most of 166 metabolites compared to young volunteers (mean age: 38.8 years old). Fifteen compounds were significantly reduced with the progression of underwater exercise.

conclusionImprovement of upright balance function with underwater exercise is correlated with several salivary components.

Indexed as

HalitosisPersons with DisabilitiesAdultAgedAged, 80 and overAmino AcidsExerciseHumansSalivaAmino Acidsamino acidhalitosismetabolomicsoral bacteriasalivaUnderwater exercise

Identifiers

PMID36309405
PMCPMC9677773
OpenAlexW4307843308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.