Evidence map›Paper›PMID 36309403›Full record

ArticleIn vivo (Athens, Greece)

Early Palliative Care Improves Overall Survival in Patients With Lymphoma: A Single-institution Retrospective Study.

Misaki Morisaku, Kaori Ito, Tatsuki Shimomura, Shoko Maeda, Maiko Mori, Seira Toyosato, Yosuke Ando, Takenao Koseki, Masami Kawahara, Akihiro Tomita and 1 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Misaki Morisaku *Department of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Kaori Ito *Department of Clinical Pharmacy, Fujita Health University, Toyoake, Japan; itoka@fujita-hu.ac.jp.
Tatsuki ShimomuraDepartment of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Shoko MaedaSchool of Pharmacy, Aichi Gakuin University, Nagoya, Japan.
Maiko MoriDepartment of Pharmacy, Fujita Health University Hospital, Toyoake, Japan.
Seira ToyosatoDepartment of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Yosuke AndoDepartment of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Takenao KosekiDepartment of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Masami KawaharaSchool of Pharmacy, Aichi Gakuin University, Nagoya, Japan.
Akihiro TomitaDepartment of Hematology, Fujita Health University School of Medicine, Toyoake, Japan.
Shigeki YamadaDepartment of Clinical Pharmacy, Fujita Health University, Toyoake, Japan.
Fujita Health University · JPAichi Gakuin University · JPFujita Health University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimEarly palliative care (EPC) intervention in patients with solid tumors can provide many benefits. However, studies on patients with hematological malignancies are limited, and there is no data on patients with lymphoma. We conducted a preliminary retrospective survey of palliative care (PC) intervention in patients with lymphoma to clarify the effect of EPC on overall survival (OS). PATIENTS AND

methodsThe first palliative care consultation (PC1) was retrospectively reviewed from medical records in Japan. Patients with lymphoma requiring inpatient PC at our institution from January 2012 to December 2018 were recruited. We conducted receiver operating characteristic (ROC) analysis; patients were divided into two groups (early and delayed), and the survival periods and palliative care team (PCT) referral details were compared.

resultsThe analysis included 77 patients with lymphoma [median age, 71 (64-79)] years. The median period to PC1 from the initial diagnosis was 395 (180-1,086) days. ROC analysis revealed an optimal PC intervention timing of 140 days. OS was significantly longer in the early group than that in the delayed group. The most common counseling details for the PCT were symptom relief and palliative care transfer (36.8% and 35.2%, respectively).

conclusionThis real-world evaluation of PC intervention for inpatients with lymphoma revealed that PC intervention was provided at approximately 13 months following initial diagnosis. EPC intervention from diagnosis to 140 days may improve OS in patients with lymphoma; however further large-scale studies are required to verify this finding.

Indexed as

LymphomaNeoplasmsAgedHumansPalliative CareRetrospective Studiesearly interventionlymphomaoverall survivalPalliative care

Identifiers

PMID36309403
PMCPMC9677750
OpenAlexW4307842785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.