Evidence map›Paper›PMID 36309379›Full record

ArticleIn vivo (Athens, Greece)

Prognostic Impact of Quality and Distribution of Adipose Tissue in Patients With Primary Central Nervous System Lymphoma.

Mattes Hinnerichs, Vincenzo Ferraro, Vanja Zeremski, Dimitrios Mougiakakos, Jazan Omari, Maciej Pech, Caroline Bär, Andreas Wienke, Sylvia Saalfeld, Alexandra Strobel and 3 more

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mattes HinnerichsDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Vincenzo FerraroDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Vanja ZeremskiDepartment of Hematology and Oncology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Dimitrios MougiakakosDepartment of Hematology and Oncology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Jazan OmariDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Maciej PechDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Caroline BärDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.
Andreas WienkeInstitute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Sylvia SaalfeldDepartment for Simulation and Graphics, University of Magdeburg, Magdeburg, Germany.
Alexandra StrobelInstitute of Medical Epidemiology, Biostatistics, and Informatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Alexey SurovDepartment of Radiology and Nuclear Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany; Alexey.Surov@med.ovgu.de.
Hans Jonas Meyer *Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Denise Wolleschak *Department of Hematology and Oncology, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimBody composition assessment has shown promising results as a prognostic biomarker as depicted by cross-sectional imaging of several tumor entities including lymphomas. The present study sought to elucidate the prognostic relevance of subcutaneous and visceral fat tissue (SAT and VAT) in patients with primary central nervous system lymphoma (PCNSL). PATIENTS AND

methodsOverall, 74 patients (36 female patients, 46.7%) with a mean age of 64.2±12.8 years (range=23-81 years) were identified in the database with sufficient clinical and imaging data and included into this retrospective study. Fat area assessment was performed on one axial slide on L3-height derived from staging computed tomography (CT) images. Subcutaneous, visceral, and intramuscular adipose tissues (SAT, VAT, IMAT) were estimated. Also, density of SAT, VAT, and IMAT were estimated. Finally, the ratio VAT/SAT (VSR) was calculated. Overall and progression-free survival (OS and PFS) were used as study end points.

resultsIn the observation period, overall, 47 patients (63.5%) died. Mean OS was 33.8±45.4 months and mean PFS was 26.6±42.7 months. The mean VAT value was 162±99.5 cm

conclusionParameters of adipose tissue are not associated with OS and PFS in patients with PCNSL.

Indexed as

Adipose TissueIntra-Abdominal FatAgedCentral Nervous SystemFemaleHumansMiddle AgedPrognosisRetrospective StudiesSubcutaneous FatBody compositioncerebral lymphomaCTvisceral fat tissue

Identifiers

PMID36309379
PMCPMC9677753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.