Evidence map›Paper›PMID 36309377›Full record

ArticleIn vivo (Athens, Greece)

Weekly Rapid Antigen Test Screening for COVID-19 in Patients on Hemodialysis.

Gaetano Alfano, Roberta Scarmignan, Alessio Amurri, Francesco Fontana, Silvia Giovanella, Giulia Ligabue, William Gennari, Monica Pecorari, Mario Sarti, Giovanni Guaraldi and 4 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Gaetano AlfanoNephrology, Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy; gaetano.alfano@unimore.it.ORCID https://orcid.org/0000-0003-0591-8622
Roberta ScarmignanSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
Alessio AmurriSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
Francesco FontanaNephrology, Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Silvia GiovanellaSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
Giulia LigabueSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
William GennariVirology and Molecular Microbiology Unit, University Hospital of Modena, Modena, Italy.
Monica PecorariVirology and Molecular Microbiology Unit, University Hospital of Modena, Modena, Italy.
Mario SartiClinical Microbiology Unit, University Hospital of Modena, Modena, Italy.
Giovanni GuaraldiClinic of Infectious Diseases, University Hospital of Modena, Modena, Italy.
Gianni CappelliSurgical, Medical and Dental Department of Morphological Sciences, Section of Nephrology, University of Modena and Reggio Emilia, Modena, Italy.
Mariacristina GregoriniNephrology and Dialysis, AUSL-IRCCS Reggio Emilia, Reggio Emilia, Italy.
Riccardo MagistroniNephrology, Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
Gabriele DonatiNephrology, Dialysis and Transplant Unit, University Hospital of Modena, Modena, Italy.
University of Modena and Reggio Emilia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimCOVID-19 is a concerning issue among in-center hemodialysis (HD) patients. To prevent COVID-19 diffusion in our HD facility, weekly rapid nasal antigen test screening was performed for all asymptomatic patients on chronic HD. This study aimed to assess the performance of weekly rapid antigen test in detecting SARS-CoV-2 infection among asymptomatic patients receiving HD. PATIENTS AND

methodsA retrospective analysis was conducted in HD patients who underwent rapid antigen test screening from December 2021 to March 2022. The diagnosis of COVID-19 with rapid antigen test was always confirmed by reverse transcriptase-polymerase chain reaction (RT-PCR).

resultsDuring the observational period, 1,748 rapid antigen tests were performed in 220 HD patients. Mean age was 68.4±14.6 years. Fifteen (8.5%) patients resulted positive for SARS-CoV-2 infection using rapid antigen tests. The diagnosis was subsequently confirmed in 14 (93.3%) patients by RT-PCR. During the same period, 12 (5.4%) symptomatic patients, regularly screened with weekly rapid antigen test, resulted positive for SARS-CoV-2 infection using RT-PCR. Overall, weekly rapid antigen test screening identified 14 out of 26 (53.8%) COVID-19 cases and showed a positive predictive value of 93%.

conclusionWeekly antigen test screening of asymptomatic patients on chronic HD detected around half of the COVID-19 cases in our population.

Indexed as

COVID-19AgedAged, 80 and overCOVID-19 TestingHumansMiddle AgedRenal DialysisRetrospective StudiesSARS-CoV-2Sensitivity and SpecificitycoronavirusCOVID-19COVID-19 testingdialysishemodialysisPCRpolymerase chain reactionRapid antigen testSARS-CoV-2screening

Identifiers

PMID36309377
PMCPMC9677751
OpenAlexW4307842371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.