Evidence map›Paper›PMID 36309317›Full record

ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2022

Genomic evolution of SARS-CoV-2 in Reunion Island.

David A Wilkinson, Alizé Mercier, Magali Turpin, Marie-Alice Simbi, Jonathan Turpin, Camille Lebarbenchon, Maya Cesari, Marie-Christine Jaffar-Bandjee, Laurence Josset, Luce Yemadje-Menudier and 2 more

Abstract read
In one paragraph

Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. New Phenolic Lipids from the Leaves ofMolecules (Basel, Switzerland) · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David A WilkinsonUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France; GIP CYROI, Saint-Denis, La Réunion, France. Electronic address: david.wilkinson@univ-reunion.fr.
Alizé MercierSanté Publique France, Saint-Denis, La Réunion, France.
Magali TurpinUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France.
Marie-Alice SimbiUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France; GIP CYROI, Saint-Denis, La Réunion, France.
Jonathan TurpinUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France; GIP CYROI, Saint-Denis, La Réunion, France.
Camille LebarbenchonUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France.
Maya CesariGIP CYROI, Saint-Denis, La Réunion, France.
Marie-Christine Jaffar-BandjeeLaboratoire de Microbiologie, Centre Hospitalier Universitaire de la Réunion, Saint-Denis, France.
Laurence JossetCNR des Virus des Infections Respiratoires, Institut des Agents Infectieux, Hospices Civils de Lyon, Lyon, France; Virpath, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, CNRS UMR5308, École Normale Supérieure de Lyon, UCBL, Lyon, France.
Luce Yemadje-MenudierSanté Publique France, Saint-Denis, La Réunion, France.
Bruno LinaCNR des Virus des Infections Respiratoires, Institut des Agents Infectieux, Hospices Civils de Lyon, Lyon, France; Virpath, Centre International de Recherche en Infectiologie, Université de Lyon, Inserm U1111, CNRS UMR5308, École Normale Supérieure de Lyon, UCBL, Lyon, France.
Patrick MavinguiUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) CNRS 9192, INSERM 1187, IRD 249, Sainte-Clotilde, La Réunion, France. Electronic address: patrick.mavingui@cnrs.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Island communities are interesting study sites for microbial evolution during epidemics, as their insular nature reduces the complexity of the population's connectivity. This was particularly true on Reunion Island during the first half of 2021, when international travel was restricted in order to mitigate the risk for SARS-CoV-2 introductions. Concurrently, the SARS-CoV-2 Beta variant became dominant and started to circulate at high levels for several months before being completely replaced by the Delta variant as of October 2021. Here, we explore some of the particularities of SARS-CoV-2 genomic evolution within the insular context of Reunion Island. We show that island isolation allowed the amplification and expansion of unique genetic lineages that remained uncommon across the globe. Islands are therefore potential hotspots for the emergence of new genetic variants, meaning that they will play a key role in the continued evolution and propagation of COVID-19 as the pandemic persists.

Indexed as

COVID-19SARS-CoV-2GenomicsHumansPandemicsEvolutionGenomicsReunion IslandSARS-CoV-2

Identifiers

PMID36309317
PMCPMC9598258

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.