ArticleDevelopmental cognitive neuroscience2022
Pubertal development underlies optimization of inhibitory control through specialization of ventrolateral prefrontal cortex.
Article in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The Effect of Pubertal Status on Self-Regulation of Behavior and Executive Functions-A Systematic Review.Developmental psychobiology · 2025Pooled it
- A protocol for the Teen Bugs study: An integrative, multi-omics approach to understanding the role of the gut microbiome and mesocorticolimbic system in adolescent mental health following early adverse caregiving.Brain, behavior, & immunity - health · 2026Article
- Neural focalization of dorsolateral prefrontal cortex and the inferior parietal lobule is associated with inhibitory control performance in adolescence.Developmental cognitive neuroscience · 2026Article
- Neurobehavioral correlates of inhibitory control in youth at-risk for early low-level alcohol use initiation: neuroimaging findings from the ABCD study.Frontiers in psychiatry · 2026Article
- Sexual Orientation, Pubertal Timing, Inhibitory Control, and Adolescent Depressive Symptoms: A Birth Cohort Study.Archives of sexual behavior · 2025Article
- Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry.Cell reports · 2025Article
- Adolescent maturation of dorsolateral prefrontal cortex glutamate:GABA and cognitive function is supported by dopamine-related neurobiology.Molecular psychiatry · 2025Article
- Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective.Developmental cognitive neuroscience · 2025Article
- The influence of relative pubertal maturity on executive function development in adolescent girls.Scientific reports · 2024Article
- Prefrontal Excitation/ Inhibition Balance Supports Adolescent Enhancements in Circuit Signal to Noise Ratio.bioRxiv : the preprint server for biology · 2024Article
- Mental Disorders, Social Media Addiction, and Academic Performance in Romanian Undergraduate Nursing Students.Journal of clinical medicine · 2024Article
- Impact of stress on excitatory and inhibitory markers of adolescent cognitive critical period plasticity.Neuroscience and biobehavioral reviews · 2023Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
Inhibitory control improves into young adulthood after specialization of relevant brain systems during adolescence. However, the biological mechanisms supporting this unique transition are not well understood. Given that adolescence is defined by puberty, we examined relative contributions of chronological age and pubertal maturation to inhibitory control development. 105 8-19-year-olds completed 1-5 longitudinal visits (227 visits total) in which pubertal development was assessed via self-reported Tanner stage and inhibitory control was assessed with an in-scanner antisaccade task. As expected, percentage and latency of correct antisaccade responses improved with age and pubertal stage. When controlling for pubertal stage, chronological age was distinctly associated with correct response rate. In contrast, pubertal stage was uniquely associated with antisaccade latency even when controlling for age. Chronological age was associated with fMRI task activation in several regions including the right dorsolateral prefrontal cortex, while puberty was associated with right ventrolateral prefrontal cortex (VLPFC) activation. Furthermore, task-related connectivity between VLPFC and cingulate was associated with both pubertal stage and response latency. These results suggest that while age-related developmental processes may support maturation of brain systems underlying the ability to inhibit a response, puberty may play a larger role in the effectiveness of generating cognitive control responses.
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