Evidence map›Paper›PMID 36308664›Full record

ReviewInternational urology and nephrology2023

An update review on hemodynamic instability in renal replacement therapy patients.

Abdullah B Yildiz, Sezan Vehbi, Andreea Covic, Alexandru Burlacu, Adrian Covic, Mehmet Kanbay

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Observational
  5. Observational
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Abdullah B YildizDepartment of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Sezan VehbiDepartment of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Andreea CovicDepartment of Nephrology, Grigore T. Popa' University of Medicine, Iasi, Romania.
Alexandru BurlacuDepartment of Nephrology, Grigore T. Popa' University of Medicine, Iasi, Romania.
Adrian CovicDepartment of Nephrology, Grigore T. Popa' University of Medicine, Iasi, Romania.
Mehmet KanbayDivision of Nephrology, Department of Medicine, Koc University School of Medicine, 34010, Istanbul, Turkey. drkanbay@yahoo.com.ORCID http://orcid.org/0000-0002-1297-0675
Grigore T. Popa University of Medicine and Pharmacy · ROKoç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodynamic instability in patients undergoing kidney replacement therapy (KRT) is one of the most common and essential factors influencing mortality, morbidity, and the quality of life in this patient population.

methodDecreased cardiac preload, reduced systemic vascular resistance, redistribution of fluids, fluid overload, inflammatory factors, and changes in plasma osmolality have all been implicated in the pathophysiology of hemodynamic instability associated with KRT.

resultA cascade of these detrimental mechanisms may ultimately cause intra-dialytic hypotension, reduced tissue perfusion, and impaired kidney rehabilitation. Multiple parameters, including dialysate composition, temperature, posture during dialysis sessions, physical activity, fluid administrations, dialysis timing, and specific pharmacologic agents, have been studied as possible management modalities. Nevertheless, a clear consensus is not reached.

conclusionThis review includes a thorough investigation of the literature on hemodynamic instability in KRT patients, providing insight on interventions that may potentially minimize factors leading to hemodynamic instability.

Indexed as

HypotensionQuality of LifeHemodynamicsHumansKidneyRenal DialysisRenal Replacement TherapyAcute kidney injuryChronic kidney diseaseDialysisHemodynamic instabilityIntradialytic hypotensionKidney replacement therapy

Identifiers

PMID36308664
OpenAlexW4307584982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.