ArticleArchives of osteoporosis2022
Low vertebral CT Hounsfield units: a risk factor for new osteoporotic vertebral fractures after the treatment of percutaneous kyphoplasty.
Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Risk factors for new vertebral compression fracture following percutaneous vertebral augmentation: a systematic review and meta-analysis based on multivariate logistic regression analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Risk factors for new vertebral fracture after percutaneous vertebroplasty or kyphoplasty for osteoporotic vertebral compression fractures (OVCFs): an updated systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- Article
- CALLY index and bone mineral density as risk factors for adjacent vertebral fracture after balloon kyphoplasty for treatment of osteoporotic vertebral compression fracture: a retrospective analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Hounsfield unit measurements from different regions of interest in lumbar spine CT: correlation with DEXA-derived bone mineral density and fracture status.BMC musculoskeletal disorders · 2026Article
- Sarcopenia Versus Systemic Inflammation as Predictors of New Vertebral Fractures After Vertebroplasty or Kyphoplasty: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- The Integrated Nerve, Discoligamentous Complex, and Vertebra Scoring System for Thoracolumbar Junction (TLJ) Injury.Orthopaedic surgery · 2026Article
- Clinical Characteristics and a New Classification System of Mono-Segmental Thoracic and Lumbar Nonfusion in Patients With Ankylosing Spondylitis.Orthopaedic surgery · 2026Article
- Diagnostic Value of Opportunistic CT-Based Bone Density Assessment in Patients with and Without Sacral Insufficiency Fractures.Diagnostics (Basel, Switzerland) · 2025Article
- Incidence of New Fractures in Patients Treated with Kyphoplasty/Vertebroplasty or Conservative Methods.Medicina (Kaunas, Lithuania) · 2025Article
- CT- and MRI-based endplate osteoporosis status assessment for predicting adjacent vertebral fractures after thoracolumbar percutaneous kyphoplasty: a matched comparison study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Effects of lumbar degeneration on the global and regional bone mineral density in osteoporotic patients requiring lumbar interbody fusion for degenerative lumbar diseases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Vertebral CT Hounsfield units in postmenopausal women with osteoporotic vertebral compression fracture: identification and validation of reference intervals.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Opportunistic Osteoporosis Assessment and Fracture Risk Determination Using Cancellous Density Measurement in Hounsfield Units of Native Lumbar Computed Tomography Images-A Comparative Study with Conventional Bone Density Evaluation.Journal of clinical medicine · 2025Article
- Evaluation of Cancellous Bone Density from C3 to L5 in 11 Body Donors: CT Versus Micro-CT Measurements.Journal of clinical medicine · 2025Article
- Does Baseline Hounsfield Unit Predict Patients' Outcomes Following Surgical Management of Unstable Osteoporotic Thoracolumbar Fractures?Medicina (Kaunas, Lithuania) · 2025Article
- [Comparative evaluation of trabecular bone density in Hounsfield units in the lumbar native CT cross-section for osteoporosis diagnosis and fracture risk determination by different examiners].Orthopadie (Heidelberg, Germany) · 2025Article
- Age-stratified association between serum uric acid and lumbar bone mineral density in elderly Chinese women with vertebral compression fractures: a cross-sectional analysis.Frontiers in medicine · 2025Article
- Answer to the letter to the editor of H. Hirata, et al. concerning "Osteoporosis screening using QCT-based cutoff values of Hounsfield units in patients with degenerative lumbar diseases" by D. Zou, et al. (Eur Spine J [2024]: doi: 10.1007/s00586-024-08491-4).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Feasibility study in quantitative identification of fresh and old osteoporotic vertebral compression fracture by vertebral CT value and CT value difference.BMC musculoskeletal disorders · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposesTo identify the characteristics of the vertebral HU in the elderly patient with new osteoporosis vertebral compression fractures (OVCF) after treatment of percutaneous kyphoplasty (PKP), which may help us to preliminarily evaluate the risk of a new OVCF after the treatment of PKP.
methodsWe retrospectively analyzed the patients who received PKP treatments in our hospital to find out the patients suffered new OVCFs after the treatment of PKP and set an age-, sex-, first fracture vertebrae-, surgical segment-, and comorbidity-matched control group without new fractures. We measured the axial and sagittal L1-HU values to compare their differences.
resultsThere were 32 patients who suffered new OVCFs and received another PKP surgery in our department. In the study group, the average L1 sagittal and axial HU values were 46.17 ± 21.31 HU and 47.77 ± 22.38 HU, and they had no statistical difference (P > 0.05). For the control group, the average L1 sagittal and axial HU values were 75.69 ± 29.72 HU and 80.23 ± 30.26 HU, and their difference was not significant (P > 0.05). No matter from the axial or sagittal evaluation, the L1 HU value in the study group was significantly lower than that in the control group (P < 0.001). The AUC of using the L1 axial HU value to differentiate patients with new fractures from controls was 0.85 while the sagittal one was 0.82. In axial (and sagittal) evaluation, the cutoff value (adjusted to the multiple of five) had high specificity of 90% or high sensitivity of 90% to identify patients with new fractures of 45 HU and 75 HU (50 HU and 75 HU), respectively.
conclusionsThe lower the vertebral HU value is, the more likely the patients suffer new OVCFs after PKP treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.