Evidence map›Paper›PMID 36308429›Full record

ReviewRheumatology (Oxford, England)2023

Comprehensive and reliable sonographic assessment and scoring system for inflammatory lesions of the paediatric ankle.

Patricia Vega-Fernandez, Deirdre De Ranieri, Edward Oberle, Matthew Clark, Hulya Bukulmez, Clara Lin, Susan Shenoi, Akaluck Thatayatikom, Leandra Woolnough, Heather Benham and 8 more

Open access · hybridAbstract readReview
In one paragraph

Review in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Is palpation essential in the digital era of orthotic designing?Frontiers in bioengineering and biotechnology · 2026
    Article
  3. Sonographic and Disease Activity Findings Related With Medication Change in JIA: A Historical Cohort Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 2 countries.

Patricia Vega-FernandezDivision of Rheumatology, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0002-4911-7256
Deirdre De RanieriDivision of Rheumatology, Department of Pediatrics, Northwestern Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital, Chicago, IL, USA.
Edward OberleDepartment of Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA.
Matthew ClarkDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Hulya BukulmezDivision of Pediatric Rheumatology, Department of Pediatrics, Metro Health Medical System, Case Western Reserve University, Cleveland, OH, USA.
Clara LinDepartment of Pediatrics, Children's Hospital Colorado, Aurora, CO, USA.
Susan ShenoiSeattle Children's Hospital and Research Center University of Washington, Seattle, WA, USA.
Akaluck ThatayatikomAdventHealth Medical Group Pediatric Rheumatology and Immunology, Orlando, FL, USA.
Leandra WoolnoughDepartment of Pediatrics, UFHealth, Gainesville, FL, USA.
Heather BenhamDepartment of Pediatrics, Scottish Rite for Children, Frisco, TX, USA.
Emily BrunnerDepartment of Pediatrics, Geisinger Medical Center, Danville, PA, USA.
Michael HenricksonDivision of Rheumatology, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Laura R PrattDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Jean-Philippe Proulx-GauthierCHU de Québec-Université Laval, Québec, Canada.
Ginger JanowJoseph M. Sanzari Children's Hospital, Hackensack, NJ, USA.
Amy CassedyDivision of Biostatistics and Epidemiology, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Tracy V TingDivision of Rheumatology, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Johannes RothChildren's Hospital Eastern Ontario, Ottawa, Canada.
Cincinnati Children's Hospital Medical Center · USChildren's Hospital Colorado · USChildren's Hospital of Eastern Ontario · CAFlorida Hospital Medical Group · USGeisinger Medical Center · USLurie Children's Hospital · USMetroHealth · USNationwide Children's Hospital · USSeattle Children's Hospital · USSt. Joseph’s Children’s Hospital · USTexas Scottish Rite Hospital for Children · USUniversité Laval · CAUniversity of Florida Health · USUniversity of Nebraska Medical Center · USVanderbilt University Medical Center · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
KL2 Training ProgramKL2TR001426 · NCATS · UNIVERSITY OF CINCINNATI · PI ZELLER, MARGARET H · 2015 to 2024
$6.8M
Pediatric musculOskeletal & RheumaTology Innovation COre center (PORTICO)P30AR076316 · NIAMS · CINCINNATI CHILDRENS HOSP MED CTR · PI BRUNNER, HERMINE I · 2019 to 2023
$3.4M
NCATS NIH HHS UL1 TR001425
6 · The paper itself

Abstract

objectiveThe clinical decision-making process in paediatric arthritis lacks an objective, reliable bedside imaging tool. The aim of this study was to develop a US scanning protocol and assess the reliability of B-mode and Doppler scoring systems for inflammatory lesions of the paediatric ankle.

methodsAs part of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) US group, 19 paediatric rheumatologists through a comprehensive literature review developed a set of standardized views and scoring systems to assess inflammatory lesions of the synovial recesses as well as tendons of the paediatric ankle. Three rounds of scoring of still images were followed by one practical exercise. Agreement among raters was assessed using two-way single score intraclass correlation coefficients (ICC).

resultsOf the 37 initially identified views to assess the presence of ankle synovitis and tenosynovitis, nine views were chosen for each B-mode and Doppler mode semi-quantitative evaluation. Several scoring exercises and iterative modifications resulted in a final highly reliable scoring system: anterior tibiotalar joint ICC: 0.93 (95% CI 0.92, 0.94), talonavicular joint ICC: 0.86 (95% CI 0.81, 0.90), subtalar joint ICC: 0.91 (95% CI 0.88, 0.93) and tendons ICC: 0.96 (95% CI 0.95, 0.97).

conclusionA comprehensive and reliable paediatric ankle US scanning protocol and scoring system for the assessment of synovitis and tenosynovitis were successfully developed. Further validation of this scoring system may allow its use as an outcome measure for both clinical and research applications.

Indexed as

Arthritis, RheumatoidSynovitisTenosynovitisAnkleChildHumansReproducibility of ResultsUltrasonographyanklediagnostic imagingJIAmusculoskeletal ultrasound

Identifiers

PMID36308429
PMCPMC10234197
OpenAlexW4307584259

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.