Evidence map›Paper›PMID 36308344›Full record

SynthesisAsian Pacific journal of cancer prevention : APJCP2022

Association of Handgrip Strength with Quality of Life in Breast Cancer Survivors: A Systematic Review and Meta-Analysis.

Alana Cristina Campos E Silva, Anke Bergmann, Camilla Medeiros Araujo, Andrea Karla Soares Montenegro, Angelica Da Silva Tenorio, Diego Dantas

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Asian Pacific journal of cancer prevention : APJCP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  5. Article
  6. Handgrip strength assessment in breast cancer patients: validity and reliability of the Activ5 dynamometer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alana Cristina Campos E SilvaFederal University of Pernambuco. Graduate program of Physical Therapy. Recife-PE, Brazil.ORCID 0000-0001-5916-4876
Anke BergmannClinical Epidemiology Program, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil.ORCID 0000-0002-1972-8777
Camilla Medeiros AraujoFederal University of Pernambuco. Graduate program of Physical Therapy. Recife-PE, Brazil.ORCID 0000-0003-0492-5329
Andrea Karla Soares MontenegroFederal University of Pernambuco. Graduate program of Physical Therapy. Recife-PE, Brazil.ORCID 0000-0001-8498-6097
Angelica Da Silva TenorioFederal University of Pernambuco. Graduate program of Physical Therapy. Recife-PE, Brazil.ORCID 0000-0002-7066-9047
Diego DantasFederal University of Pernambuco. Graduate program of Physical Therapy. Recife-PE, Brazil.ORCID 0000-0002-1966-3352
Instituto Nacional do Câncer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHandgrip strength (HGS) is an indicator of general muscular strength and in cancer patients acts as a relevant marker associated with mortality and health. This study aimed to evaluate the association between peripheral muscle function and health-related quality of life (HRQoL) in breast cancer (BC) survivors.

methodsSystematic review registered on PROSPERO under number: CRD 42021225206. The searches were carried out on MEDLINE via Pubmed, PEDro, Cochrane Library, Embase, CINAHL via EBSCO and Science Direct databases. Observational studies evaluating the association between handgrip strength (HGS) and HRQoL in adult female BC survivors were included. No linguistic or time restrictions were applied. Two reviewers reviewed full texts for inclusion and performed data extraction and risk of bias using the Newcastle and Ottawa scale (NOS).

resultsFive articles were included and involved 587 patients, mean age of 47 to 59 years. The percentage of decreased HGS ranged from 38.3% to 60.3%. HGS was associated with different quality of life measures. From meta-analysis including 220 patients, the correlation coefficient between HGS and HRQoL was 0.26 (95% CI: 0.07-0.35).

conclusionsBreast cancer survivors face decline of HGS. In this population HGS was correlated with HRQoL. However, more evidence are necessary.

Indexed as

Breast NeoplasmsCancer SurvivorsAdultFemaleHand StrengthHumansMiddle AgedQuality of LifeSurvivorsBreast Neoplasmclinical evaluationhand strengthmuscle strengthquality of life indicators

Identifiers

PMID36308344
PMCPMC9924335
OpenAlexW4307808722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.