Evidence map›Paper›PMID 36307819›Full record

ArticleLipids in health and disease2022

Distribution of lipid levels and prevalence of hyperlipidemia: data from the NHANES 2007-2018.

Zhenhan Li, Guoqi Zhu, Guo Chen, Mei Luo, Xuebo Liu, Zhongpei Chen, Jun Qian

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 81 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Metabolites · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhenhan LiDepartment of Endocrinology, Chongqing Hospital Of Traditional Chinese Medicine, Chongqing, China.
Guoqi ZhuDepartment of Cardiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Guo ChenDepartment of Endocrinology, Chongqing Hospital Of Traditional Chinese Medicine, Chongqing, China.
Mei LuoDepartment of Endocrinology, Chongqing Hospital Of Traditional Chinese Medicine, Chongqing, China.
Xuebo Liu *Department of Cardiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Zhongpei Chen *Department of Endocrinology, Chongqing Hospital Of Traditional Chinese Medicine, Chongqing, China.
Jun Qian *Department of Cardiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China. jgsqianjun@163.com.
First People's Hospital of Chongqing · CNTongji University · CNTongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLipid-lowering therapy is important, and the distribution of lipid levels and the incidence of hyperlipidemia may vary in different subgroups of the population. We aimed to explore the distribution of lipid levels and the prevalence of hyperlipidemia in subpopulations with subgroup factors, including age, sex, race, and smoking status.

methodsOur study used data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018, ultimately enrolling and analyzing 15,499 participants. A cross-sectional analysis was performed to assess the distribution of lipids and prevalence of hyperlipidemia in subpopulations, and multifactorial logistic regression analyses were performed for the prevalence of hyperlipidemia, adjusted for age, sex, race and smoking status.

resultsBlacks had significantly lower mean serum total cholesterol and triglycerides and higher serum high-density lipoprotein cholesterol (HDL-C) than whites (P < 0.001). In contrast, Mexican Americans had markedly higher mean serum triglycerides and lower serum HDL-C than whites (P < 0.001). Furthermore, the prevalence of hypercholesterolemia and hypertriglyceridemia was lower in blacks than in whites (P = 0.003 and P < 0.001, respectively), while the prevalence of hypertriglyceridemia was significantly higher in Mexican Americans than in whites (P = 0.002). In addition, total cholesterol and triglyceride levels were significantly higher in women aged 65 years or older and markedly higher than in men in the same age group (P < 0.001). In addition, overall mean total cholesterol, triglyceride, and low-density lipoprotein cholesterol (LDL-C) levels were higher in smokers than in nonsmokers (P = 0.01, P < 0.001, and P = 0.005, respectively).

conclusionBased on NHANES data, the mean lipid levels and prevalence of hyperlipidemia differed by sex, age, race, and smoking status.

Indexed as

HyperlipidemiasHypertriglyceridemiaCholesterol, HDLCross-Sectional StudiesFemaleHumansMaleNutrition SurveysPrevalenceTriglyceridesCholesterol, HDLTriglyceridesAgeHyperlipidemiaLipid levelsNHANES databaseRaceSexSmoking status

Identifiers

PMID36307819
PMCPMC9615374
OpenAlexW4307455040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.