Evidence map›Paper›PMID 36307783›Full record

ArticleBMC musculoskeletal disorders2022

All-cause mortality risk in older patients with femoral neck fracture.

Xin-Ping Li, Ping Zhang, Shi-Wen Zhu, Ming-Hui Yang, Xin-Bao Wu, Xie-Yuan Jiang

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xin-Ping LiDepartment of Geriatrics, Beijing Jishuitan Hospital, 100035, Beijing, China.
Ping ZhangDepartment of Geriatrics, Beijing Jishuitan Hospital, 100035, Beijing, China.
Shi-Wen ZhuDepartment of Orthopaedic and Traumatology, Beijing Jishuitan Hospital, 100035, Beijing, China.
Ming-Hui YangDepartment of Orthopaedic and Traumatology, Beijing Jishuitan Hospital, 100035, Beijing, China. doctyang0125@126.com.
Xin-Bao WuDepartment of Orthopaedic and Traumatology, Beijing Jishuitan Hospital, 100035, Beijing, China.
Xie-Yuan JiangDepartment of Orthopaedic and Traumatology, Beijing Jishuitan Hospital, 100035, Beijing, China.
Peking University · CNBeijing Jishuitan Hospital · CN

Funding

Beijing Municipal Administration of Hospitals Incubating Program PX 2019015Beijing Municipal Health Committee Scientific Research Project Beijing 19-17Capital's Funds for Health Improvement and Research 2022-1-2071
6 · The paper itself

Abstract

introductionThe mortality rate after hip fracture is high. However, the 1-year mortality rate after femoral intertrochanteric fracture and femoral neck fracture differs (Gibson-Smith D, Klop C, Elders PJ, Welsing PM, van Schoor N, Leufkens HG, et al., Osteoporos Int 25:2555-2563, 2014), although both are types of hip fracture. A previous real-world single-center prospective cohort study showed that older age and high Charlson comorbidity index score were risk factors for femoral intertrochanteric fracture. Additionally, therapy with zoledronic acid 5 mg (Aclasta) was a protective factor (Li XP, Zhang P, Zhu SW, Yang MH, Wu XB, Jiang XY, J Orthop Surg Res. 16:727, 2021). We wished to determine the risk factors for all-cause mortality in femoral neck fracture patients.

aimTo identify the risk factors for postoperative all-cause mortality in aged patients with femoral neck fracture. MATERIALS AND

methodsWe enrolled 307 aged patients with femoral neck fracture; 38 were lost to follow-up after 2-3 years. The patients' general characteristics, bone mineral density, and anti-osteoporosis treatment after operation were recorded as potential risk factors. Kaplan-Meier curves and multivariate Cox proportional hazards models were constructed to analyze the influence of each factor on all-cause mortality.

resultsThis was a real-world single-center prospective cohort study showing that (1) most of the patients who died were male, older (mean age of the patients who died: 84.8 years vs. 77.9 years for survivors), and had more comorbidities compared with surviving patients. Previous fracture history, body mass index, femoral neck T score, hemoglobin and 25-hydroxy vitamin D levels did not differ significantly between patients who died vs. survived. (2) Differing from patients with intertrochanteric fractures, older patients with femoral neck fracture experienced no reduction in all-cause mortality with treatment with zoledronic acid.

conclusionIn Chinese patients with femoral neck fracture, physicians should pay careful attention to male patients, older patients, and those with high numbers of comorbidities.

Indexed as

Femoral FracturesFemoral Neck FracturesHip FracturesAgedAged, 80 and overFemaleFemur NeckHumansMaleProspective StudiesRisk FactorsZoledronic AcidZoledronic AcidFemoral neck fractureMortalityOsteoporosis

Identifiers

PMID36307783
PMCPMC9615195
OpenAlexW4307714099

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.