Evidence map›Paper›PMID 36307657›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2022

Perceived social support declines after deep brain stimulation surgery in patients with Parkinson's disease.

Sydney Spagna, Asra Askari, Kara J Wyant, Laura Zeitlin, Taylor R Schmitt, Carol C Persad, Xiru Lyu, Parag G Patil, Kelvin L Chou

Abstract read
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Article in Journal of neural transmission (Vienna, Austria : 1996), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sydney SpagnaDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA. syspagna@med.umich.edu.ORCID 0000-0003-2397-7001
Asra AskariSurgical Therapies Improving Movement Program, Ann Arbor, MI, USA.
Kara J WyantDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Laura ZeitlinSurgical Therapies Improving Movement Program, Ann Arbor, MI, USA.
Taylor R SchmittDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Carol C PersadDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Xiru LyuDepartment of Statistics, University of Michigan, Ann Arbor, MI, USA.
Parag G PatilDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
Kelvin L ChouDepartment of Neurology, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Social Provisions Scale (SPS) measures a person's perceived social support. We evaluated the perceived social support in Parkinson's disease (PD) patients before and after subthalamic nucleus (STN) deep brain stimulation (DBS) and its impact on clinical outcomes following DBS.

methodsWe analyzed 55 PD patients who underwent STN DBS surgery and completed the SPS, PDQ-39, and MDS-UPDRS Parts I-IV before and 6-12 months after surgery. Some patients also completed global cognitive, mood and apathy scales. Caregivers completed the CBI at each visit. Linear regression models and linear mixed models evaluated the association between the SPS baseline score, MDS-UPDRS and PDQ-39 scores, the association between MDS-UPDRS, CBI and the SPS follow-up score, and the association between SPS, global cognition and other psychological variables.

resultsDBS implantation improved MDS-UPDRS I-IV and PDQ-39 scores. Perceived social support declined after DBS (baseline SPS total 82.55 ± 7.52 vs. follow-up SPS total 78.83 ± 9.02, p = 0.0001). Baseline SPS total score was not significantly associated with the MDS-UPDRS or PDQ-39 scores at follow-up. MDS-UPDRS scores and the CBI at follow-up had no significant association with SPS total score at follow-up. Measures of global cognition, mood and apathy were associated with the SPS before and after DBS, and the association was independent of STN DBS.

conclusionAfter STN DBS, PD patients experienced a decrease in perceived social support, but baseline perceived social support did not impact clinical outcomes. It is important to further identify factors that may contribute to this perception of worsened social support.

Indexed as

Deep Brain StimulationParkinson DiseaseSubthalamic NucleusHumansSocial SupportTreatment OutcomeDeep brain stimulationParkinson’s diseaseSocial Provisions ScaleSocial support

Identifiers

PMID36307657
OpenAlexW4307580981

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.