Evidence map›Paper›PMID 36307412›Full record

ArticleNature communications2022

Effective screening of Coulomb repulsions in water accelerates reactions of like-charged compounds by orders of magnitude.

Adam Kowalski, Krzysztof Bielec, Grzegorz Bubak, Pawel J Żuk, Maciej Czajkowski, Volodymyr Sashuk, Wilhelm T S Huck, Jan M Antosiewicz, Robert Holyst

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Adam Kowalski *Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, 01-224, Poland.ORCID 0000-0003-0172-2622
Krzysztof Bielec *University of Zurich, Department of Chemistry, Zurich, CH-8057, Switzerland.ORCID 0000-0002-6023-5499
Grzegorz Bubak *Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, 01-224, Poland.ORCID 0000-0001-7938-4016
Pawel J ŻukInstitute of Physical Chemistry, Polish Academy of Sciences, Warsaw, 01-224, Poland.ORCID 0000-0003-0555-5913
Maciej CzajkowskiUniversity of Oxford, Department of Chemistry, Oxford, OX1 3TA, UK.
Volodymyr SashukInstitute of Physical Chemistry, Polish Academy of Sciences, Warsaw, 01-224, Poland. vsashuk@ichf.edu.pl.ORCID 0000-0002-5907-8596
Wilhelm T S HuckInstitute for Molecules and Materials, Radboud University, Nijmegen, 6525 AJ, Netherlands. w.huck@science.ru.nl.ORCID 0000-0003-4222-5411
Jan M AntosiewiczInstitute of Experimental Physics, Biophysics Division, University of Warsaw, Warsaw, 02-093, Poland. jantosi@fuw.edu.pl.ORCID 0000-0002-9269-2192
Robert HolystInstitute of Physical Chemistry, Polish Academy of Sciences, Warsaw, 01-224, Poland. rholyst@ichf.edu.pl.ORCID 0000-0002-3211-4286

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reaction kinetics between like-charged compounds in water is extremely slow due to Coulomb repulsions. Here, we demonstrate that by screening these interactions and, in consequence, increasing the local concentration of reactants, we boost the reactions by many orders of magnitude. The reaction between negatively charged Coenzyme A molecules accelerates ~5 million-fold using cationic micelles. That is ~10

Indexed as

MicellesWaterCationsKineticsPolymersSodium ChlorideCationsMicellesPolymersSodium ChlorideWater

Identifiers

PMID36307412
PMCPMC9616817

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.