Evidence map›Paper›PMID 36307154›Full record

ArticleBMJ open2022

Cohort profile: a prospective Australian cohort study of women's reproductive characteristics and risk of chronic disease from menarche to premenopause (M-PreM).

Hsiu-Wen Chan, Shyamali Dharmage, Annette Dobson, Hsin-Fang Chung, Deborah Loxton, Jenny Doust, Grant Montgomery, Emmanuel Stamatakis, Rachel R Huxley, Mark Hamer and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 3 countries.

Hsiu-Wen ChanSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-1545-0488
Shyamali DharmageAllergy and Lung Health Unit, School of Population and Global Health, The University of Melbourne, Carlton, Victoria, Australia.
Annette DobsonSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia.
Hsin-Fang ChungSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia.
Deborah LoxtonCentre for Women's Health Research, The University of Newcastle, Newcastle, New South Wales, Australia.
Jenny DoustSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia.
Grant MontgomeryInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Emmanuel StamatakisCharles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.
Rachel R HuxleyFaculty of Health, Deakin University, Burwood, Victoria, Australia.
Mark HamerDivision of Surgery and Interventional Sciences, Faculty of Medical Sciences, University College London, London, UK.
Jason AbbottSchool of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-4406-3121
Bu Beng YeapMedical School, The University of Western Australia, Perth, Western Australia, Australia.
Jenny A VisserDepartment of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Harold McIntyreSchool of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Gregore Iven MielkeSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia.
Gita D MishraSchool of Public Health, The University of Queensland, Brisbane, Queensland, Australia G.Mishra@uq.edu.au.
The University of Queensland · AUDeakin University · AUErasmus MC · NLRoyal Hospital for Women · AUThe University of Melbourne · AUThe University of Sydney · AUThe University of Western Australia · AUUniversity College London · GBUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrevious studies have identified associations between individual reproductive factors and chronic disease risk among postmenopausal women. However, few have investigated the association of different markers of reproductive function, their interactions and risk factors of chronic disease among women approaching menopause. The Menarche-to-PreMenopause (M-PreM) Study aims to examine the relationship between reproductive factors across the reproductive lifespan and risk indicators for chronic disease among women in their early-to-mid-40s. The purpose of this cohort profile paper is to describe the rationale, study design and participant characteristics of the M-PreM Study.

participantsWomen born in 1973-1978 who participated in the Australian Longitudinal Study on Women's Health (ALSWH) were invited to undertake a clinical or self-administered assessment. A total of 1278 women were recruited from June 2019 to June 2021. FINDINGS TO DATE: The study measures included functional, cognitive and cardiometabolic tests, anthropometry, spirometry, respiratory health questionnaires, physical activity, sleep patterns, sex hormones, and cardiovascular and metabolic markers; whereas blood and saliva samples were used for the analysis of genetic variants of genes associated with reproductive characteristics and chronic disease. The mean age of the clinic and self-assessed participants was 44.6 and 45.3 years, respectively. The menopausal status of participants was similar between the two arms of the study: 38%-41% premenopausal, 20% perimenopausal, and 36% took oral contraception or hormone replacement therapy. Approximately 80% of women had at least one child and participants reported experiencing pregnancy complications: preterm birth (8%-13% of pregnancies), gestational diabetes (10%) and gestational hypertension (10%-15%). FUTURE PLANS: The biomedical data collected in the M-PreM Study will be linked to existing ALSWH survey data on sociodemographic factors, health behaviour, reproductive function, and early life factors collected over the past 20 years and health administrative data. The association between reproductive factors and risk indicators of chronic disease will be analysed.

Indexed as

MenarchePremature BirthAdultAustraliaChildChronic DiseaseCohort StudiesFemaleHumansInfant, NewbornLongitudinal StudiesMenopauseMiddle AgedPerimenopausePregnancyPremenopauseAsthmaEPIDEMIOLOGYHypertensionPUBLIC HEALTH

Identifiers

PMID36307154
PMCPMC9621184
OpenAlexW4307468413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.