Evidence map›Paper›PMID 36307136›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2022

Five-Year Symptom Trajectories in Nondialysis-Dependent CKD Patients.

Moustapha Faye, Karine Legrand, Lisa Le Gall, Karen Leffondre, Abdou Y Omorou, Natalia Alencar de Pinho, Christian Combe, Denis Fouque, Christian Jacquelinet, Maurice Laville and 8 more

Open access · greenAbstract read
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Health-related quality of life in kidney transplant recipients: association with graft function and comparison to patients on dialysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Chronic kidney disease.Nature reviews. Disease primers · 2025
    Review
  13. Review
  14. Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Article
  15. Health-related quality of life and symptom burden in patients on haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Moustapha FayeCHRU-Nancy, Nancy, France moustapha439.faye@ucad.edu.sn.ORCID 0000-0001-5321-9741
Karine LegrandCHRU-Nancy, Nancy, France.ORCID 0000-0003-0209-4576
Lisa Le GallUniversity of Bordeaux, Bordeaux, France.
Karen LeffondreUniversity of Bordeaux, Bordeaux, France.
Abdou Y OmorouCHRU-Nancy, Nancy, France.
Natalia Alencar de PinhoParis-Saclay University, Villejuif, France.ORCID 0000-0002-0438-6487
Christian CombeService de Néphrologie Transplantation Dialyse Aphérèse, Bordeaux, France.ORCID 0000-0002-0360-573X
Denis FouqueService de Néphrologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, France.ORCID 0000-0002-9707-7199
Christian JacquelinetAgence de la Biomédecine, La Plaine Saint-Denis, France.
Maurice LavilleUniversité Claude Bernard Lyon 1, Pierre-Bénite, France.
Sophie LiabeufDépartement de Recherche Clinique, Amiens, France.ORCID 0000-0001-5384-9006
Ziad A MassyParis-Saclay University, Villejuif, France.ORCID 0000-0001-5771-5996
Elodie SpeyerParis-Saclay University, Villejuif, France.ORCID 0000-0002-2152-0051
Roberto Pecoits FilhoArbor Research Collaborative for Health, Ann Arbor, Michigan.ORCID 0000-0002-0255-6710
Bénédicte StengelParis-Saclay University, Villejuif, France.
Luc FrimatUniversité de Lorraine, Nancy, France.
Carole Ayav
CKD-REIN Study Group
Université de Bordeaux · FRUniversité de Lorraine · FRUniversité Paris-Saclay · FRAgence de la Biomédecine · FRHôpital Lyon Sud · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesLate stages of CKD are characterized by significant symptom burden. This study aimed to identify subgroups within the 5-year trajectories of symptom evolution in patients with CKD and to describe associated patient characteristics and outcomes. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Among 2787 participants (66% men) with eGFR <60 ml/min per 1.73 m

resultsPatient mean age (±SD) at baseline was 67±13 years, and mean eGFR was 33±13 ml/min per 1.73 m

conclusionsThis study highlights a significant worsening of symptoms in about one third of the participants, whereas the majority reported low symptom severity throughout the study.

Indexed as

Renal Insufficiency, ChronicAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle AgedQuality of LifeRisk FactorsSurveys and QuestionnairesCKDclinical epidemiologycohort studiesquality of lifesymptoms

Identifiers

PMID36307136
PMCPMC9718050
OpenAlexW4307582517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.