Evidence map›Paper›PMID 36306799›Full record

ArticleAmerican journal of speech-language pathology2022

Screening for Autism in 2-Year-Old Children: The Application of the Systematic Observation of Red Flags to the Screening Tool for Autism in Toddlers and Young Children.

Tara Rooney, Yael S Stern, Lauren H Hampton, Jeffrey Grauzer, Amanda Hobson, Amy Levin, Maranda K Jones, Aaron J Kaat, Megan Y Roberts

Abstract read
In one paragraph

Article in American journal of speech-language pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tara RooneyRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.
Yael S SternRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.ORCID 0000-0002-8041-3985
Lauren H HamptonDepartment of Special Education, The University of Texas at Austin.ORCID 0000-0002-7016-1067
Jeffrey GrauzerRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.ORCID 0000-0001-6202-9851
Amanda HobsonRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.ORCID 0000-0001-8065-145X
Amy LevinRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.
Maranda K JonesRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.ORCID 0000-0001-8357-9350
Aaron J KaatDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL.ORCID 0000-0001-8147-1899
Megan Y RobertsRoxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.ORCID 0000-0002-4699-0236

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
The role of parent phenotype in parent-mediated language interventions for autismR01DC014709 · NIDCD · NORTHWESTERN UNIVERSITY · PI ROBERTS, MEGAN Y · 2015 to 2019
$3.7M
NCATS NIH HHS UL1 TR001422NIDCD NIH HHS R01 DC014709
6 · The paper itself

Abstract

purposeA multimeasure approach was developed to capitalize on the strengths of two screening measures: the Screening Tool for Autism in Toddlers and Young Children (STAT), an observational measure of social communication, and the Systematic Observation of Red Flags (SORF), a checklist including restricted and repetitive behavior (RRB) items. This approach offers a novel method of identifying autism in toddlers.

methodThis was a retrospective study of data collected from a multidisciplinary diagnostic program for 24- to 36-month-olds with developmental delays. Raters with autism expertise but naïve to diagnoses applied the SORF to STAT videos. Psychometrics were derived for the SORF on STAT observations and a multiple-measure approach that used a Least Absolute Shrinkage and Selection Operator modeling framework to construct a STAT-SORF RRB Hybrid, retaining SORF RRB items based on individual predictive abilities.

resultsThe SORF alone correctly classified 84% of the sample (84% sensitivity and 86% specificity). The STAT-SORF RRB Hybrid model, which retained four SORF RRB items, correctly classified 90% of a validation sample (95% sensitivity and 75% specificity).

conclusionThese findings highlight the potential utility of using multiple autism identification tools and regression-based scoring to establish presumptive eligibility and facilitate early access to autism interventions.

Indexed as

Autism Spectrum DisorderAutistic DisorderChild, PreschoolHumansMass ScreeningPsychometricsRetrospective Studies

Identifiers

PMID36306799
PMCPMC9911122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.