Evidence map›Paper›PMID 36306401›Full record

ReviewBrain and behavior2022

COVID-19 and myasthenia gravis: A review of neurological implications of the SARS-COV-2.

Syed Muhammad Ismail Shah, Farah Yasmin, Roha Saeed Memon, Nadia Nazir Jatoi, Ilma Saleh Savul, Sana Kazmi, Syed Abdullah Monawwer, Muhammad Daim Bin Zafar, Muhammad Sohaib Asghar, Muhammad Junaid Tahir and 1 more

Abstract readReview
In one paragraph

Review in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Double-seropositive Myasthenia Gravis Following COVID-19.Internal medicine (Tokyo, Japan) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Neuro-ophthalmic sequelae post-COVID-19.Indian journal of ophthalmology · 2023
    Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Syed Muhammad Ismail ShahDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Farah YasminDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Roha Saeed MemonDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Nadia Nazir JatoiDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Ilma Saleh SavulDepartment of Internal Medicine, St. Joseph Medical Center, Houston, Texas, USA.
Sana KazmiDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Syed Abdullah MonawwerDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Muhammad Daim Bin ZafarDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Muhammad Sohaib AsgharDepartment of Internal Medicine, Dow University Ojha Hospital, Karachi, Pakistan.ORCID 0000-0001-6705-2030
Muhammad Junaid TahirLahore General Hospital, Lahore, Pakistan.
Ka Yiu LeeSwedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.ORCID 0000-0001-5577-0940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis review highlights the potential mechanisms of neuromuscular manifestation of COVID-19, especially myasthenia gravis (MG).

methodsAn extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020.

resultsExacerbations of clinical symptoms in patients of MG who were treated with some commonly used COVID-19 drugs has been reported, with updated recommendations of management of symptoms of neuromuscular disorders. Severe acute respiratory syndrome coronavirus 2 can induce the immune response to trigger autoimmune neurological disorders.

conclusionsFurther clinical studies are warranted to indicate and rather confirm if MG in the setting of COVID-19 can pre-existent subclinically or develop as a new-onset disease.

Indexed as

COVID-19Myasthenia GravisHumansSARS-CoV-2Guillain-Barre syndromeimmunoglobulinsinfectionmyasthenia gravispyridostigmine bromidesevere acute respiratory syndrome coronavirus 2

Identifiers

PMID36306401
PMCPMC9759145

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.