ArticleThe international journal of cardiovascular imaging2023
Decreased left atrial function in obesity patients without known cardiovascular disease.
Article in The international journal of cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Obesity effect on newly diagnosed and recurrent post-ablation atrial fibrillation: a systematic review and meta-analysis.Journal of endocrinological investigation · 2024Pooled it
- Effect of glycemic status on the natural history of left atrial structure and function in adults with metabolic syndrome and obesity.International journal of cardiology · 2026Observational
- Left Atrial Remodeling and Functional Maladaptations in Obesity: An Invasive Pressure-Volume Analysis.Circulation. Heart failure · 2026Article
- Early Effects of Bariatric Surgery on Reversing Obesity-Induced Heart Dysfunction.Obesity surgery · 2026Article
- Glycemic status and left atrial structure and function in adults with metabolic syndrome and overweight-obesity.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice.Reviews in cardiovascular medicine · 2025Review
- Proarrhythmogenic Echocardiographic Markers in Metabolic Syndrome: A Cross-Sectional Study.Life (Basel, Switzerland) · 2025Article
- Obesity-induced left atrial dysfunction across age groups and cardiovascular conditions: a comprehensive review of diagnostic advances and clinical implications.Annals of translational medicine · 2025Review
- Diagnosing Heart Failure with Preserved Ejection Fraction in Obese Patients.Journal of clinical medicine · 2025Review
- Challenges in the diagnosis of heart failure with preserved ejection fraction in individuals with obesity.Cardiovascular diabetology · 2025Review
- Relationship Between Left Atrial Strain and Atrial Fibrillation: The Role of Stress Echocardiography.Diagnostics (Basel, Switzerland) · 2024Review
- Exploring risk Indicators of atrial fibrillation in severe Obesity: Left atrial cardiomyopathy and premature atrial contractions.International journal of cardiology. Heart & vasculature · 2024Article
- Mediating Effect of the NLR on the Relationship Between HbA1c and Left Atrial Stiffness in Overweight Patients With Hypertension.American journal of hypertension · 2024Article
- The Clinical Applications of Left Atrial Strain: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
- The effect of body weight on left atrial function determined by longitudinal strain analysis in young adults.The international journal of cardiovascular imaging · 2024Article
- Improved identification of left atrial enlargement in patients with obesity.The international journal of cardiovascular imaging · 2024Article
- Interaction effect of hypertension and obesity on left atrial phasic function: a three-dimensional echocardiography study.Quantitative imaging in medicine and surgery · 2023Article
- Impact of body mass index on worsening of diastolic function and impairment of left atrial strain in the general female urban population: a subanalysis of the Berlin female risk evaluation echocardiography follow-up study.Frontiers in cardiovascular medicine · 2023Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a risk factor for heart failure with preserved ejection fraction (HFpEF). We hypothesized that assessment of left atrial (LA) strain may be useful to reveal precursors of HFpEF in obesity patients. Echocardiograms of obesity patients without known cardiovascular disease who underwent bariatric surgery, and echocardiograms of age- and gender matched controls were analyzed. The echocardiogram was repeated 1 year after bariatric surgery. LA reservoir strain (LASr), LA conduit strain (LAScd), and LA contractile strain (LASct) were measured. 77 Obesity patients were compared with 46 non-obese controls. Obesity patients showed a significantly decreased LA function compared with non-obese individuals (LASr 32.2% ± 8.8% vs. 39.6% ± 10.8%, p < 0.001; LAScd 20.1% ± 7.5% vs. 24.9% ± 8.3%, p = 0.001; LASct 12.1% ± 3.6% vs. 14.5% ± 5.5%, p = 0.005). There was no difference in prevalence of diastolic dysfunction between the obesity group and controls (9.1% vs. 2.2%, p = 0.139). One year after bariatric surgery, LASr improved (32.1% ± 8.9% vs. 34.2% ± 8.7%, p = 0.048). In the multivariable linear regression analysis, BMI was associated with LASr, LAScd, and LASct (β = - 0.34, CI - 0.54 to - 0.13; β = - 0.22, CI - 0.38 to - 0.06; β = - 0.10, CI - 0.20 to - 0.004). Obesity patients without known cardiovascular disease have impairment in all phases of LA function. LA dysfunction in obesity may be an early sign of cardiac disease and may be a predictor for developing HFpEF. LASr improved 1 year after bariatric surgery, indicating potential reversibility of LA function in obesity.
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