Evidence map›Paper›PMID 36306020›Full record

ReviewCurrent cardiology reports2022

Posttraumatic Stress Disorder (PTSD) as a Risk Factor for Cardiovascular Disease: Implications for Future Research and Clinical Care.

Anita S Hargrave, Jennifer A Sumner, Ramin Ebrahimi, Beth E Cohen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current cardiology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Cardiac Rehabilitation Among Veterans: A Narrative Review.Journal of cardiopulmonary rehabilitation and prevention · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anita S HargraveDepartment of Internal Medicine, University of California San Francisco (UCSF), San Francisco, CA, 94110, USA. Anita.Hargrave@ucsf.edu.ORCID 0000-0002-9717-5282
Jennifer A SumnerDepartment of Psychology, University of California Los Angeles (UCLA), Los Angeles, CA, 90095-1563, USA.
Ramin EbrahimiDepartment of Medicine, Cardiology Section, Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, CA, USA.
Beth E CohenDepartment of Internal Medicine, University of California San Francisco (UCSF), San Francisco, CA, 94110, USA.
University of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

Identifying Early Intervention Targets for Reducing Cardiovascular Risk in Posttraumatic StressR01HL139614 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SUMNER, JENNIFER A · 2018 to 2022
$3.9M
Identifying Cardiotoxic Manifestations of Posttraumatic Psychopathology: A Population-based Longitudinal InvestigationR01HL160850 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GRADUS, JAIMIE L., SUMNER, JENNIFER A · 2022 to 2025
$2.6M
HRSA HHS T32HP19025NHLBI NIH HHS R01 HL139614NHLBI NIH HHS R01HL139614NHLBI NIH HHS R01 HL160850NHLBI NIH HHS R01HL160850
6 · The paper itself

Abstract

purpose of reviewPosttraumatic stress disorder (PTSD) may be an important risk factor for cardiovascular disease (CVD). We explore the literature linking PTSD to CVD, potential mechanisms, interventions, and clinical implications. We outline gaps in current literature and highlight necessary future research. RECENT

findingsPTSD has been independently associated with deleterious effects on cardiovascular health through biological, behavioral, and societal pathways. There are evidence-based psychotherapeutic interventions and pharmacotherapies for PTSD that may mitigate its impact on CVD. However, there are limited studies that rigorously analyze the impact of treating PTSD on cardiovascular outcomes. Trauma-informed CVD risk stratification, education, and treatment offer opportunities to improve patient care. These approaches can include a brief validated screening tool for PTSD identification and treatment. Pragmatic trials are needed to test PTSD interventions among people with CVD and evaluate for improved outcomes.

Indexed as

Cardiovascular DiseasesStress Disorders, Post-TraumaticHumansRisk FactorsCardiac risk factorsCardiovascular diseaseCVDPosttraumatic stress disorderPTSDRisk factors

Identifiers

PMID36306020
PMCPMC12726747
OpenAlexW4307501995

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.