Evidence map›Paper›PMID 36305868›Full record

ArticleLab on a chip2022

Multiplexed microfluidic platform for stem-cell derived pancreatic islet β cells.

Ishan Goswami, Eleonora de Klerk, Phichitpol Carnese, Matthias Hebrok, Kevin E Healy

Abstract read
In one paragraph

Article in Lab on a chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Bioengineering gradients for controlled embryo and organ modeling.Current opinion in biomedical engineering · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ishan GoswamiDepartment of Bioengineering and California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, CA 94720, USA. kehealy@berkeley.edu.ORCID 0000-0002-7097-7656
Eleonora de KlerkDiabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
Phichitpol CarneseDiabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
Matthias HebrokDiabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
Kevin E HealyDepartment of Bioengineering and California Institute for Quantitative Biosciences (QB3), University of California Berkeley, Berkeley, CA 94720, USA. kehealy@berkeley.edu.ORCID 0000-0002-8524-3671

Funding

Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes MellitusUH3DK120004 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, HEBROK, MATTHIAS · 2020 to 2022
$6.9M
Microphysiological systems to interrogate the Islet-Liver-Adipose Axis in normal physiology and Type-2 Diabetes MellitusUG3DK120004 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI HEALY, KEVIN EDWARD, HEBROK, MATTHIAS · 2018 to 2019
$2.3M
NIDDK NIH HHS UG3 DK120004NIDDK NIH HHS UH3 DK120004
6 · The paper itself

Abstract

Stem cell-derived β cells offer an alternative to primary islets for biomedical discoveries as well as a potential surrogate for islet transplantation. The expense and challenge of obtaining and maintaining functional stem cell-derived β cells calls for a need to develop better high-content and high-throughput culture systems. Microphysiological systems (MPS) are promising high-content

Indexed as

Insulin-Secreting CellsIslets of LangerhansInsulinInsulin SecretionMicrofluidicsStem CellsInsulin

Identifiers

PMID36305868
PMCPMC9642094

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.