Evidence map›Paper›PMID 36305668›Full record

ArticleContact dermatitis2023

Use of sorbitan sesquioleate in patch test preparations and patch testing with the substance-What do our results mean?

Thanisorn Sukakul, Magnus Bruze, Martin Mowitz, Cecilia Svedman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contact dermatitis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thanisorn SukakulDepartment of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0002-5351-2988
Magnus BruzeDepartment of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0002-2919-3227
Martin MowitzDepartment of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0001-6172-9274
Cecilia SvedmanDepartment of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.ORCID https://orcid.org/0000-0003-4797-0269
Lund University · SE

Funding

Edvard Welanders Stiftelse 802008-1082Finsenstiftelsen 813600-1701Fundraising Foundation HudFonden 802478-8476HudFonden
6 · The paper itself

Abstract

backgroundSorbitan sesquioleate (SSO) is a sorbitan fatty acid ester, an emulsifier used in topical products and certain patch test preparations. SSO may affect the patch test results. It has been debated whether to include the substance in the baseline series to avoid misinterpretation of the results.

objectivesTo report the prevalence and simultaneous reactions of SSO with other patch test preparations containing SSO as an emulsifier. MATERIALS AND

methodsA retrospective analysis of 3539 dermatitis patients who underwent patch testing from 2016 to 2020 was performed.

resultsThe 5-year SSO contact allergy prevalence was 0.48%, and 1.3% had a doubtful reaction. Patients with a stronger positive reaction (2+, 3+) were more likely to react simultaneously to other allergen preparations containing SSO (p value = 0.018). One patient with a strong reaction to SSO reacted positively to all SSO-containing patch test preparations. Definite fragrance allergens could not be identified in the patients who had simultaneous reactions to SSO and fragrance mix (FM) I.

conclusionsPatch testing with allergen preparations containing SSO affected the patch test interpretation. Fragrance contact allergy could not be ruled out when a patient simultaneously reacted to SSO and FM I. Changing emulsifiers in patch test preparations would be advantageous.

Indexed as

Dermatitis, Allergic ContactPerfumeAllergensEmulsifying AgentsHexosesHumansPatch TestsRetrospective StudiesTest Taking SkillsAllergensEmulsifying AgentsHexosesPerfumesorbitan sesquioleate2-hydroxyethyl methacrylateatopic dermatitisdecyl glucosideemulsifierEvernia prunastri (oakmoss) extractfragrance contact allergyfragrance mixMyroxylon pereirae resinpatch test preparationssorbitan sesquioleate

Identifiers

PMID36305668
PMCPMC10092872
OpenAlexW4307464981

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.