Evidence map›Paper›PMID 36305518›Full record

ArticlePharmaceutical biology2022

Ameliorative effect of chitosan nanoparticles against carbon tetrachloride-induced nephrotoxicity in Wistar rats.

Yousra A Nomier, Saeed Alshahrani, Mahmoud Elsabahy, Gihan F Asaad, Azza Hassan, Walaa A El-Dakroury

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  3. Manganese Deficiency and MnInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Yousra A NomierPharmacology and Toxicology Department, Pharmacy College, Jazan University, Jazan, Saudi Arabia.
Saeed AlshahraniPharmacology and Toxicology Department, Pharmacy College, Jazan University, Jazan, Saudi Arabia.ORCID 0000-0002-9626-219X
Mahmoud ElsabahySchool of Biotechnology and Science Academy, Badr University in Cairo, Badr City, Cairo, Egypt.
Gihan F AsaadDepartment of Pharmacology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt.
Azza HassanPathology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Walaa A El-DakrouryDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo, Badr City, Cairo, Egypt.
Badr University in Cairo · EGJazan University · SACairo University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextChitosan is a biocompatible polysaccharide that has been widely exploited in biomedical and drug delivery applications.

objectiveThis study explores the renoprotective effect of chitosan nanoparticles MATERIALS AND

methodsChitosan nanoparticles were prepared via ionotropic gelation method, and several

resultsMonodisperse spherical nanosized (56 nm) particles were successfully prepared as evidenced by dynamic light scattering and TEM. Oral administration of chitosan nanoparticles (10 and 20 mg/kg) concurrently with CCl

conclusionsChitosan nanoparticles afforded significant protection and amelioration against CCl

Indexed as

ChitosanNanoparticlesAnimalsCarbon TetrachlorideParticle SizeRatsRats, WistarCarbon TetrachlorideChitosanCCl4drug deliveryRenoprotective

Identifiers

PMID36305518
PMCPMC9621247
OpenAlexW4307511331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.