Evidence map›Paper›PMID 36305274›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors.

Khulood H Oudah, Walaa R Mahmoud, Fadi M Awadallah, Azza T Taher, Safinaz E-S Abbas, Heba Abdelrasheed Allam, Daniela Vullo, Claudiu T Supuran

Abstract read
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In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khulood H OudahPharmaceutical Chemistry Department, College of Pharmacy, Al-Ayen University, Nasiriyah, Iraq.
Walaa R MahmoudPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Fadi M AwadallahPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Azza T TaherDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Safinaz E-S AbbasPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Heba Abdelrasheed AllamPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Daniela VulloDepartment NEUROFARBA - Pharmaceutical and Nutraceutical section, University of Firenze, Università degli Studi di Firenze, Sesto Fiorentino, Italy.
Claudiu T SupuranDepartment NEUROFARBA - Pharmaceutical and Nutraceutical section, University of Firenze, Università degli Studi di Firenze, Sesto Fiorentino, Italy.ORCID 0000-0003-4262-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present investigation reports the design and synthesis of three series of benzoylthioureido derivatives bearing either benzenesulfonamide

Indexed as

Carbonic Anhydrase InhibitorsCarbonic AnhydrasesAcetazolamideBenzenesulfonamidesCarbonic Anhydrase IXMolecular Docking SimulationMolecular StructurePhenylurea CompoundsProtein IsoformsStructure-Activity RelationshipSulfonamidesAcetazolamideBenzenesulfonamidesCarbonic Anhydrase InhibitorsCarbonic Anhydrase IXCarbonic AnhydrasesPhenylurea CompoundsProtein IsoformsSLC-0111SulfonamidesbenzenesulfonamidesCarbonic anhydraseSLC-0111zinc binding-group (ZBG)

Identifiers

PMID36305274
PMCPMC9621292

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.