ArticleInternational journal of chronic obstructive pulmonary disease2022
Functional Predictors Discriminating Asthma-COPD Overlap (ACO) from Chronic Obstructive Pulmonary Disease (COPD).
Article in International journal of chronic obstructive pulmonary disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- The Reliability of a Novel Structured Testing Device for Single-breath Lung Carbon Monoxide Uptake: A Randomized Comparison Crossover Study.BMC pulmonary medicine · 2025Trial
- Small Airway Function as an Indicator for Persistent Airflow Limitation Asthma: A Retrospective Study.The clinical respiratory journal · 2026Article
- The diagnostic value of bronchodilator response in differentiating asthma, COPD, and ACO in fixed airflow obstruction: a retrospective study.BMC pulmonary medicine · 2025Article
- Predicting parameters of airway dynamics generated from inspiratory and expiratory plethysmographic airway loops, differentiating subtypes of chronic obstructive diseases.BMJ open respiratory research · 2024Article
- The value of bronchodilator response in FEV1 and FeNO for differentiating between chronic respiratory diseases: an observational study.European journal of medical research · 2024Observational
- Assessment of functional diversities in patients with Asthma, COPD, Asthma-COPD overlap, and Cystic Fibrosis (CF).PloS one · 2024Article
- A multifactorial model for chronic obstructive pulmonary disease risk in smokers with positive bronchodilation: a retrospective cohort study.Therapeutic advances in respiratory diseaseArticle
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Abstract
Background: A significant proportion of patients with obstructive lung disease have clinical and functional features of both asthma and chronic obstructive pulmonary disease (COPD), referred to as the asthma-COPD overlap (ACO). The distinction of these phenotypes, however, is not yet well-established due to the lack of defining clinical and/or functional criteria. The aim of our investigations was to assess the discriminating power of various lung function parameters on the assessment of ACO. Methods: From databases of 4 pulmonary centers, a total of 540 patients (231 males, 309 females), including 372 patients with asthma, 77 patients with ACO and 91 patients with COPD, were retrospectively collected, and gradients among combinations of explanatory variables of spirometric (FEV Results: LDA revealed that parameters of airway dynamics (sWOB, sR Conclusion: The complexity of COPD with its components of interaction and their heterogeneity, especially in discrimination from ACO, may well be differentiated if patients are explored by a whole set of target parameters evaluating, interactionally, flow limitation, airway dynamics, pulmonary hyperinflation, small airways dysfunction and gas exchange disturbances assessing specific functional deficits.
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