Evidence map›Paper›PMID 36304817›Full record

Trial reportJournal of nutritional science2022

Enhanced bioavailability and pharmacokinetics of a novel hybrid-hydrogel formulation of fisetin orally administered in healthy individuals: a randomised double-blinded comparative crossover study.

Illathu Madhavamenon Krishnakumar, Asha Jaja-Chimedza, Ashil Joseph, Abhilash Balakrishnan, Balu Maliakel, Andrew Swick

Abstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of nutritional science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  17. The Emerging Role of Senolysis in Atherosclerosis.Medicina (Kaunas, Lithuania) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Illathu Madhavamenon KrishnakumarR & D Centre Akay Natural Ingredients, Ambunad, Malaidamthuruth P. O., Cochin, Kerala 683561, India.
Asha Jaja-ChimedzaLife Extension, 3600 W Commercial Blvd, Fort Lauderdale, FL 33309, USA.
Ashil JosephR & D Centre Akay Natural Ingredients, Ambunad, Malaidamthuruth P. O., Cochin, Kerala 683561, India.
Abhilash BalakrishnanR & D Centre Akay Natural Ingredients, Ambunad, Malaidamthuruth P. O., Cochin, Kerala 683561, India.
Balu MaliakelR & D Centre Akay Natural Ingredients, Ambunad, Malaidamthuruth P. O., Cochin, Kerala 683561, India.
Andrew SwickLife Extension, 3600 W Commercial Blvd, Fort Lauderdale, FL 33309, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

FlavonolsHydrogelsBiological AvailabilityCross-Over StudiesHealthy VolunteersHumansfisetinFlavonolsHydrogelsBioavailabilityFenugreek galactomannansFenumatFisetinFlavonoidsPharmacokinetics

Identifiers

PMID36304817
PMCPMC9574875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.