Evidence map›Paper›PMID 36304703›Full record

ReviewFrontiers in reproductive health2020

When Can We Safely Stop Luteal Phase Support in Fresh IVF Cycles? A Literature Review.

Yossi Mizrachi, Arieh Raziel, Ariel Weissman

Abstract readReview
In one paragraph

Review in Frontiers in reproductive health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yossi MizrachiIn vitro Fertilization Unit, Department of Obstetrics and Gynecology, The Edith Wolfson Medical Center, Holon, Affiliated With Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Arieh RazielIn vitro Fertilization Unit, Department of Obstetrics and Gynecology, The Edith Wolfson Medical Center, Holon, Affiliated With Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Ariel WeissmanIn vitro Fertilization Unit, Department of Obstetrics and Gynecology, The Edith Wolfson Medical Center, Holon, Affiliated With Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no consensus on the optimal duration of luteal phase support (LPS) in fresh IVF cycles. Although some clinicians withdraw LPS on the day of a positive pregnancy test, most clinicians continue its administration at least up to the 8th week of gestation. In this literature review, we included several randomized clinical trials comparing early and late cessation of LPS. Most studies have found no benefit in extended administration. These studies, however, were limited by their small sample size and selection bias. Until now, only a few attempts have been made to indicate when LPS can be safely stopped based on individual patient characteristics. In conclusion, the quality and quantity of the evidence regarding LPS duration in fresh IVF cycles is currently insufficient to justify early cessation in all patients. Individualization of LPS should receive high priority in future research.

Indexed as

ARTduration (time)freshIVFluteal support

Identifiers

PMID36304703
PMCPMC9580666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.