Evidence map›Paper›PMID 36304567›Full record

ArticleNewborn (Clarksville, Md.)

Enteroviral Infections in Infants.

Srijan Singh, Sushant Satish Mane, Gangajal Kasniya, Sofia Cartaya, Mohd Mujibur Rahman, Akhil Maheshwari, Mario Motta, Pradeep Dudeja

Open access · bronzeAbstract read
In one paragraph

Article in Newborn (Clarksville, Md.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Neonatal myocarditis due to Coxsackie: case report and literature review].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Srijan SinghDepartment of Pediatrics, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.ORCID 0000-0002-2103-5232
Sushant Satish ManeDepartment of Pediatrics, Grant Government Medical College and Sir JJ Group of Hospitals, Mumbai, Maharashtra, India.
Gangajal KasniyaDepartment of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York, United States of America.
Sofia CartayaDepartment of Pediatrics, University of South Florida, Tampa, Florida, United States of America.
Mohd Mujibur RahmanDepartment of Neonatology, Institute of Child and Mother Health, Dhaka, Bangladesh.
Akhil MaheshwariGlobal Newborn Society, Clarksville, Maryland, United States of America.ORCID 0000-0003-3613-4054
Mario MottaNeonatologia e Terapia Intensiva Neonatale ASST Spedali Civili di Brescia, Italy.
Pradeep DudejaDepartment of Gastroenterology, University of Illinois at Chicago, Illinois, United States of America.
Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals · INUniversity of South Florida · USAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Illinois Chicago · US

Funding

Intestinal Anion Transporters: Function and RegulationR01DK054016 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 1998 to 2022
$7.0M
Transporter Trafficking Mechanisms in Infectious DiarrheaR01DK092441 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2011 to 2020
$3.0M
Novel Role of DRA/SLC26A3 Downregulation in Gut Dysbiosis, Inflammation and InfectionR56DK092441 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2023 to 2023
$533k
Mechanisms of Regulation of Intestinal Cl Absorption in IBD Associated DiarrheaI01BX002011 · VA · JESSE BROWN VA MEDICAL CENTER · PI DUDEJA, PRADEEP K · 2013 to 2024
–
BLRD VA I01 BX002011NIDDK NIH HHS R01 DK054016NIDDK NIH HHS R01 DK092441NIDDK NIH HHS R56 DK092441
6 · The paper itself

Abstract

Enteroviruses (EVs) are major pathogens in young infants. These viruses were traditionally classified into the following four subgenera: polio, coxsackie A and B, and echoviruses. Now that poliomyelitis seems to be controlled in most parts of the world, coxsackie and echoviruses are gaining more attention because (i) the structural and pathophysiological similarities and (ii) the consequent possibilities in translational medicine. Enteroviruses are transmitted mainly by oral and fecal-oral routes; the clinical manifestations include a viral prodrome including fever, feeding intolerance, and lethargy, which may be followed by exanthema; aseptic meningitis and encephalitis; pleurodynia; myopericarditis; and multi-system organ failure. Laboratory diagnosis is largely based on reverse transcriptase-polymerase chain reaction, cell culture, and serology. Prevention and treatment can be achieved using vaccination, and administration of immunoglobulins and antiviral drugs. In this article, we have reviewed the properties of these viruses, their clinical manifestations, and currently available methods of detection, treatment, and prognosis.

Indexed as

Coxsackie virusEnterovirusesNeonateNewborn

Identifiers

PMID36304567
PMCPMC9599990
OpenAlexW4303418587

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.