Evidence map›Paper›PMID 36304539›Full record

ArticleFrontiers in cardiovascular medicine2022

Case report: Characterization of a rare pathogenic variant associated with loss of COL3A1 expression in vascular Ehlers Danlos syndrome.

Janvie Manhas, Lov Raj Lohani, Ashikh Seethy, Uma Kumar, Shivanand Gamanagatti, Sudip Sen

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Spontaneous celiac artery aneurysms in 13-year-old and 10-year-old brothers withJournal of vascular surgery cases and innovative techniques · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Janvie Manhas *Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Lov Raj Lohani *Department of Rheumatology, All India Institute of Medical Sciences, New Delhi, India.
Ashikh SeethyDepartment of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
Uma KumarDepartment of Rheumatology, All India Institute of Medical Sciences, New Delhi, India.
Shivanand GamanagattiDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Sudip SenDepartment of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vascular subtype of Ehlers Danlos Syndrome (vEDS) is a rare connective tissue disorder characterized by spontaneous arterial, bowel or organ rupture. The diagnosis of vEDS is established in a proband by identification of a heterozygous pathogenic variant in the alpha-1 gene of type III collagen (

Indexed as

clinical fibroblast testingCOL3A1 pathogenic variantexome sequencinghepatic artery dissectionstrokevascular Ehlers Danlos syndrome

Identifiers

PMID36304539
PMCPMC9595653
OpenAlexW4304614148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.