Evidence map›Paper›PMID 36304500›Full record

ReviewJournal of clinical and translational hepatology2022

Pregnancy and Metabolic-associated Fatty Liver Disease: A Clinical Update.

Sherouk Fouda, Madhu Mathew Vennikandam, Joseph M Pappachan, Cornelius J Fernandez

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Mortality and Cancer in Offspring of Mothers With Biopsy-Proven MASLD During Pregnancy: A Nationwide Cohort Study.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Sherouk FoudaSchool of Health and Biomedical Sciences, RMIT University, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0001-8227-4571
Madhu Mathew VennikandamDepartment of Gastroenterology and Hepatology, Sparrow Hospital, Michigan State University College of Human Medicine, Lansing, MI, USA.
Joseph M PappachanDepartment of Endocrinology and Metabolism, Lancashire Teaching Hospitals NHS Trust, Preston, UK.ORCID https://orcid.org/0000-0003-0886-5255
Cornelius J FernandezDepartment of Endocrinology & Metabolism, Pilgrim Hospital, Boston, UK.ORCID https://orcid.org/0000-0002-1171-5525
Manchester Metropolitan University · GBPilgrim Hospital · GBRMIT University · AUSparrow Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intricate relationship between metabolic-associated fatty liver disease (MAFLD) and maternal complications has rapidly become a significant health threat in pregnant women. The presence of MAFLD in pregnancy increases the maternal risk of metabolic complications and comorbidities for both mother and baby. The preexistence or development of MAFLD in pregnancy is a complex multifactorial disorder that can lead to further complications for mother and baby. Therefore, as pregnant women are severely underrepresented in clinical research, there is a great need for a fair inclusion of this group in clinical trials. This review aims to explore the effects of MAFLD during pregnancy in the context of maternal complications and outcomes and explore the effects of pregnancy on the development and progression of MAFLD within the context of maternal obesity, altered metabolic profiles, gestational diabetes and altered hormonal profiles. We also addressed potential implications for the presence of MAFLD during pregnancy and its management in the clinical setting.

Indexed as

Fatty liverMaternal complicationsMetabolic-associated fatty liver diseasePregnancy

Identifiers

PMID36304500
PMCPMC9547252
OpenAlexW4281562235

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.