Evidence map›Paper›PMID 36304412›Full record

ReviewFrontiers in veterinary science2022

Epidemiology, pathology, prevention, and control strategies of inclusion body hepatitis and hepatitis-hydropericardium syndrome in poultry: A comprehensive review.

Nahed A El-Shall, Hatem S Abd El-Hamid, Magdy F Elkady, Hany F Ellakany, Ahmed R Elbestawy, Ahmed R Gado, Amr M Geneedy, Mohamed E Hasan, Mariusz Jaremko, Samy Selim and 2 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 47 citations in OpenAlex.

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  19. Genomic Mosaicism in Fowl Adenovirus 3 Strains.Animals : an open access journal from MDPI · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Nahed A El-ShallPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt.
Hatem S Abd El-HamidPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Magdy F ElkadyPoultry Disease Department, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Hany F EllakanyPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Ahmed R ElbestawyPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Ahmed R GadoPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Amr M GeneedyPoultry and Fish Diseases Department, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Mohamed E HasanBioinformatic Department, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, El Sadat City, Egypt.
Mariusz JaremkoSmart-Health Initiative and Red Sea Research Center, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia.
Samy SelimDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Khaled A El-TarabilyDepartment of Biology, College of Science, United Arab Emirates University, Al-Ain, United Arab Emirates.
Mohamed E Abd El-HackPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Damanhour University · EGAlexandria University · EGAl Jouf University · SABeni-Suef University · EGKing Abdullah University of Science and Technology · SAUnited Arab Emirates University · AEUniversity of Sadat City · EGZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with fowl adenoviruses (FAdVs) can result in a number of syndromes in the production of chicken, including inclusion body hepatitis (IBH), hepatitis-hydropericardium syndrome (HHS), and others, causing enormous economic losses around the globe. FAdVs are divided into 12 serotypes and five species (A-E; 1-8a and 8b-11). Most avian species are prone to infection due to the widespread distribution of FAdV strains. The genus aviadenovirus, which is a member of the adenoviridae family, is responsible for both IBH and HHS. The most popular types of transmission are mechanical, vertical, and horizontal. Hepatitis with basophilic intranuclear inclusion bodies distinguishes IBH, but the buildup of translucent or straw-colored fluid in the pericardial sac distinguishes HHS. IBH and HHS require a confirmatory diagnosis because their clinical symptoms and postmortem abnormalities are not unique to those conditions. Under a microscope, the presence of particular lesions and inclusion bodies may provide clues. Traditional virus isolation in avian tissue culture is more delicate than in avian embryonated eggs. Additionally, aviadenovirus may now be quickly and precisely detected using molecular diagnostic tools. Preventive techniques should rely on efficient biosecurity controls and immunize breeders prior to production in order to protect progeny. This current review gives a general overview of the current local and global scenario of IBH, and HHS brought on by FAdVs and covers both their issues and preventative vaccination methods.

Indexed as

aviadenovirusdiagnosisdisease transmissionepidemicsfowl adenovirusespoultry diseasesvaccines

Identifiers

PMID36304412
PMCPMC9592805
OpenAlexW4304165622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.