Evidence map›Paper›PMID 36304301›Full record

ArticleFrontiers in bioinformatics2022

Detecting Genetic Variation of Colonizing

Yan Zhou, Xue-Chao Zhao, Lin-Qi Wang, Cheng-Wen Chen, Mei-Hua Hsu, Wan-Ting Liao, Xiao Deng, Qing Yan, Guo-Ping Zhao, Chyi-Liang Chen and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioinformatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Adaptive microevolution in CC17Frontiers in cellular and infection microbiology · 2026
    Article
  2. First Report ofMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Yan ZhouState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Xue-Chao ZhaoThe Institutes of Biology and Medical Sciences, School of Biology and Basic Medical Sciences, Soochow University, Suzhou, China.
Lin-Qi WangState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Cheng-Wen ChenShanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China.
Mei-Hua HsuMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Wan-Ting LiaoMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Xiao DengThe Institutes of Biology and Medical Sciences, School of Biology and Basic Medical Sciences, Soochow University, Suzhou, China.
Qing YanShanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China.
Guo-Ping ZhaoState Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China.
Chyi-Liang ChenMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Liang ZhangShanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China.
Cheng-Hsun ChiuMolecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Chinese National Human Genome Center at Shanghai · CNChang Gung Memorial Hospital · TWSoochow University · CNChang Gung University · TWChinese National Human Genome Center · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deciphering the genotypic diversity of within-individual pathogens and verifying the evolutionary model can help elucidate resistant genotypes, virulent subpopulations, and the mechanism of opportunistic pathogenicity. However, observed polymorphic mutations (PMs) are rare and difficult to be detected in the "dominant-lineage" model of bacterial infection due to the low frequency. The four pooled group B

Indexed as

colonizationdominant lineagegroup B Streptococcuspolymorphic mutationpooled sample

Identifiers

PMID36304301
PMCPMC9580942
OpenAlexW4281615909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.