Evidence map›Paper›PMID 36304243›Full record

SynthesisFrontiers in public health2022

Systematic review of the scientific evidence of the pulmonary carcinogenicity of talc.

Heather N Lynch, Daniel J Lauer, William J Thompson, Olivia Leleck, Rachel D Freid, Justin Collins, Kathleen Chen, A Michael Ierardi, Ania M Urban, Michael A Cappello and 2 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Heather N LynchChemRisk (Stantec), Boston, MA, United States.
Daniel J LauerChemRisk (Stantec), Boston, MA, United States.
William J ThompsonChemRisk (Stantec), Boston, MA, United States.
Olivia LeleckChemRisk (Stantec), Boston, MA, United States.
Rachel D FreidChemRisk (Stantec), Boston, MA, United States.
Justin CollinsChemRisk (Stantec), Boston, MA, United States.
Kathleen ChenChemRisk (Stantec), Boston, MA, United States.
A Michael IerardiChemRisk (Stantec), Boston, MA, United States.
Ania M UrbanChemRisk (Stantec), Boston, MA, United States.
Michael A CappelloChemRisk (Stantec), Boston, MA, United States.
Paolo BoffettaPopulation Sciences, Stony Brook Cancer Center, Stony Brook, NY, United States.
Kenneth A MundtChemRisk (Stantec), Boston, MA, United States.
Stantec (United States) · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a systematic review to assess the potential pulmonary carcinogenicity of inhaled talc in humans. Our systematic review methods adhere to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and incorporated aspects from the US Institute of Medicine (IOM) and several United States (US) Environmental Protection Agency (EPA) frameworks for systematic reviews. A comprehensive literature search was conducted. Detailed data abstraction and study quality evaluation, adapting the US Toxic Substances Control Act (TSCA) framework, were central to our analysis. The literature search and selection process identified 23 primary studies that assessed exposure to talc and pulmonary cancer risks in humans (

Indexed as

TalcAnimalsHumansUnited StatesTalccarcinogenicityhazard assessmentlung cancermesotheliomarisk assessmentsystematic reviewtalc

Identifiers

PMID36304243
PMCPMC9593030
OpenAlexW4304184068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.