ArticleAdvances in radiation oncology
Simulation-Free Radiation Therapy: An Emerging Form of Treatment Planning to Expedite Plan Generation for Patients Receiving Palliative Radiation Therapy.
Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07117032 (A Prospective Pilot Clinical Trial of Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain), which is not on this map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Pilot Clinical Trial of Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
Who cites it
30 citing papers in PubMed, 40 citations in OpenAlex.
- Workflow and dosimetric results for direct-to-unit single-fraction adaptive lung SBRT delivered on the ONE-STOP prospective pilot clinical trial.Clinical and translational radiation oncology · 2026Article
- Initial experience of clinical implementation of an Online Simulation-free CBCT-based Adaptive Radiotherapy (OSCAR) workflow for palliative and urgent treatment indications.Journal of applied clinical medical physics · 2026Article
- Development of a cost-effective end-to-end commissioning test for simulation-omitted direct-to-unit adaptive radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Streamlining Paediatric Palliative Radiotherapy: A Case Study on Reducing Procedural Burden and Avoiding General Anaesthesia Using a Simulation-Free Radiotherapy (SF-RT) Protocol.Journal of medical radiation sciences · 2026Article
- Direct-to-treatment MRI-guided prostate radiotherapy using a generic patient-agnostic reference plan.Technical innovations & patient support in radiation oncology · 2026Article
- Simulation-free spine palliative radiotherapy enabled by AI-adapted diagnostic CT.Medical physics · 2026Article
- In-Silico Trial of Same-Day Simulation-Free Spatially Fractionated Adaptive Radiotherapy (SFJournal of applied clinical medical physics · 2026Article
- Simulation-free palliative radiotherapy using diagnostic CT scans- is less more? A systematic review.Clinical and translational radiation oncology · 2026Review
- Clinical experience with a same-day simulation and treatment program for stereotactic radiation therapy on a C-arm linac.Journal of applied clinical medical physics · 2026Article
- Adaptive radiotherapy for gastrointestinal malignancies.Radiation oncology (London, England) · 2025Review
- [Simulation-free radiation therapy in palliative care].Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Simulation-free radiotherapy on the MR-linac in prostate cancer.The British journal of radiology · 2025Article
- Simulation-Free Palliative Radiation Therapy: Implementing the Value-Based and Easier-Access Model of Care in a Rural Setting.Journal of medical radiation sciences · 2025Review
- Adaptive-driven CT simulation-free multi-fraction SBRT radiotherapy: Initial clinical experience.Journal of applied clinical medical physics · 2025Article
- Magnetic resonance-only rapid on-table planning and immediate treatment for spine metastases.Physics and imaging in radiation oncology · 2025Article
- Evaluating the use of diagnostic CT with flattening filter free beams for palliative radiotherapy: Dosimetric impact of scanner calibration variability.Journal of applied clinical medical physics · 2025Article
- Article
- Development of an automated CBCT-based simulation-free platform for expedited palliative radiotherapy on a conventional linear accelerator.Journal of applied clinical medical physics · 2025Article
- Simulation-free magnetic resonance-guided radiation therapy of prostate cancer.Physics and imaging in radiation oncology · 2024Article
- Palliative radiotherapy of soft tissue tumoral masses based on diagnostic instead of planning computed tomography scans.Physics and imaging in radiation oncology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Herein we report the clinical and dosimetric experience for patients with metastases treated with palliative simulation-free radiation therapy (SFRT) at a single institution. Methods and Materials: SFRT was performed at a single institution. Multiple fractionation regimens were used. Diagnostic imaging was used for treatment planning. Patient characteristics as well as planning and treatment time points were collected. A matched cohort of patients with conventional computed tomography simulation radiation therapy (CTRT) was acquired to evaluate for differences in planning and treatment time. SFRT dosimetry was evaluated to determine the fidelity of SFRT. Descriptive statistics were calculated on all variables and statistical significance was evaluated using the Wilcoxon signed rank test and Results: Thirty sessions of SFRT were performed and matched with 30 sessions of CTRT. Seventy percent of SFRT and 63% of CTRT treatments were single fraction. The median time to plan generation was 0.88 days (0.19-1.47) for SFRT and 1.90 days (0.39-5.23) for CTRT ( Conclusions: Palliative SFRT is an emerging technique that allowed for a statistically significant lower time to plan generation and was dosimetrically acceptable. This benefit must be weighed against increased total treatment time for patients receiving SFRT compared with CTRT, and appropriate patient selection is critical.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.