Evidence map›Paper›PMID 36304091›Full record

ReviewWorld journal of gastroenterology2022

Clearance of the liver remnant predicts short-term outcome in patients undergoing resection of hepatocellular carcinoma.

Atsushi Miki, Yasunaru Sakuma, Hideyuki Ohzawa, Akira Saito, Yoshiyuki Meguro, Jun Watanabe, Kazue Morishima, Kazuhiro Endo, Hideki Sasanuma, Atsushi Shimizu and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Atsushi MikiDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan. amiki@jichi.ac.jp.
Yasunaru SakumaDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Hideyuki OhzawaDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Akira SaitoDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Yoshiyuki MeguroDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Jun WatanabeDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Kazue MorishimaDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Kazuhiro EndoDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Hideki SasanumaDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Atsushi ShimizuDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Alan Kawarai LeforDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Yoshikazu YasudaDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Naohiro SataDepartment of Surgery, Jichi Medical University, Shimotsuke 329-0498, Tochigi, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstimation of the functional reserve of the remnant liver is important to reduce morbidity and mortality.

aimTo estimate the functional reserve of the remnant liver in patients with hepatocellular carcinoma (HCC).

methodsWe reviewed the medical records of 199 patients who underwent resection of HCC. Hepatic clearance of the remnant liver was calculated using fusion images of

resultsTwenty-seven (30%) patients had major complications and 23 (12%) developed PHLF. The incidence of major complications increased with increasing albumin-bilirubin (ALBI) grade. The area under the curve values for hepatic clearance of the remnant liver, liver to heart-plus-liver radioactivity at 15 min (LHL15), and ALBI score predicting PHLF were 0.868, 0.629, and 0.655, respectively. The area under the curve for hepatic clearance of the remnant liver, LHL15, and ALBI score predicting major complications were 0.758, 0.594, and 0.647, respectively. The risk factors for PHLF and major complications were hepatic clearance of the remnant liver and intraoperative bleeding.

conclusionThe measurement of hepatic clearance may predict PHLF and major complications for patients undergoing resection of HCC.

Indexed as

Carcinoma, HepatocellularLiver FailureLiver NeoplasmsAlbuminsBilirubinHepatectomyHumansPostoperative ComplicationsRetrospective StudiesAlbuminsBilirubinCirrhosisComplicationFusion imageHepatectomyLiver functionMortality

Identifiers

PMID36304091
PMCPMC9594014
OpenAlexW4304617836

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.