Evidence map›Paper›PMID 36303977›Full record

ReviewFrontiers in reproductive health2021

Use of Moisturizers and Lubricants for Vulvovaginal Atrophy.

Ayane Cristine Alves Sarmento, Márcia Farina Kamilos, Ana Paula Ferreira Costa, Pedro Vieira-Baptista, José Eleutério, Ana Katherine Gonçalves

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in reproductive health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Laser and radiofrequency for treating genitourinary syndrome of menopause in breast cancer survivors: A systematic review of randomized controlled trial.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Pooled it
  2. Modern methods of treating vaginal dryness and atrophy.Przeglad menopauzalny = Menopause review · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ayane Cristine Alves SarmentoHealth Sciences Postgraduate Program, Federal University of Rio Grande Do Norte (UFRN), Natal, Brazil.
Márcia Farina KamilosDepartment of Gynecology, Hospital Heliópolis, São Paulo, Brazil.
Ana Paula Ferreira CostaHealth Sciences Postgraduate Program, Federal University of Rio Grande Do Norte (UFRN), Natal, Brazil.
Pedro Vieira-BaptistaLower Genital Tract Unit, Centro Hospitalar de São João, Porto, Portugal.
José EleutérioDepartment of Obstetrics and Gynecology, Federal University of Ceará, Fortaleza, Brazil.
Ana Katherine GonçalvesHealth Sciences Postgraduate Program, Federal University of Rio Grande Do Norte (UFRN), Natal, Brazil.
Universidade Federal do Rio Grande do Norte · BRHospital de São João · PTHospital Heliópolis · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The estrogen decrease in postmenopausal women results in functional and anatomical changes in the genitourinary tract. The most prevalent and bothersome symptoms are vaginal dryness, dyspareunia, and reduced lubrication, which can significantly affect the quality of life of these women, principally those who are sexually active. Hormonal therapy with local estrogens is generally considered the "gold standard." However, there are cases in which there are clinical concerns about its use or women opt for non-hormonal options. Thus, safe and effective non-hormonal options are needed to improve symptoms in these women. Moisturizers and lubricants are first-line therapy for breast cancer survivors.

Indexed as

lubricantsmenopausemoisturizersnon-hormonal treatmentvulvovaginal atrophy

Identifiers

PMID36303977
PMCPMC9580673
OpenAlexW4200260146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.