Evidence map›Paper›PMID 36303751›Full record

ArticleFrontiers in bioinformatics2021

COVID-19 Multi-Targeted Drug Repurposing Using Few-Shot Learning.

Yang Liu, You Wu, Xiaoke Shen, Lei Xie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Artificial Intelligence-Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yang LiuDepartment of Computer Science, Hunter College, The City University of New York, New York, NY, United States.
You WuThe Graduate Center, The City University of New York, New York, NY, United States.
Xiaoke ShenDepartment of Computer Science, Hunter College, The City University of New York, New York, NY, United States.
Lei XieDepartment of Computer Science, Hunter College, The City University of New York, New York, NY, United States.
City University of New York · US

Funding

Omics data integration and analysis for structure-based multi-target drug designR01GM122845 · NIGMS · NORTHEASTERN UNIVERSITY · PI Lei Xie · 2017 to 2026
$3.0M
NIGMS NIH HHS R01 GM122845
6 · The paper itself

Abstract

The life-threatening disease COVID-19 has inspired significant efforts to discover novel therapeutic agents through repurposing of existing drugs. Although multi-targeted (polypharmacological) therapies are recognized as the most efficient approach to system diseases such as COVID-19, computational multi-targeted compound screening has been limited by the scarcity of high-quality experimental data and difficulties in extracting information from molecules. This study introduces

Indexed as

deep learninggraph neural networkpolypharmacologySARS-CoV-2self-supervised learningvirtual screening

Identifiers

PMID36303751
PMCPMC9581066
OpenAlexW3167852095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.