Evidence map›Paper›PMID 36303451›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2022

Team is brain: leveraging EHR audit log data for new insights into acute care processes.

Christian Rose, Robert Thombley, Morteza Noshad, Yun Lu, Heather A Clancy, David Schlessinger, Ron C Li, Vincent X Liu, Jonathan H Chen, Julia Adler-Milstein

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Enhanced Trauma Video Review With Computer Vision: Trauma Resuscitation Phase Segmentation and Procedure Detection.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2025
    Article
  5. Primary care staff members' experiences with managing electronic health record inbox messages.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  6. Review
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  13. Quantitative and qualitative methods advance the science of clinical workflow research.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Christian RoseDepartment of Emergency Medicine, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-5115-649X
Robert ThombleyCenter for Clinical Informatics and Improvement Research, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Morteza NoshadStanford Center for Biomedical Informatics Research, Stanford University, Stanford, California, USA.
Yun LuKaiser Permanente Division of Research, Oakland, California, USA.
Heather A ClancyKaiser Permanente Division of Research, Oakland, California, USA.
David SchlessingerKaiser Permanente Division of Research, Oakland, California, USA.
Ron C LiStanford Center for Biomedical Informatics Research, Stanford University, Stanford, California, USA.
Vincent X LiuKaiser Permanente Division of Research, Oakland, California, USA.
Jonathan H ChenStanford Center for Biomedical Informatics Research, Stanford University, Stanford, California, USA.
Julia Adler-MilsteinCenter for Clinical Informatics and Improvement Research, Department of Medicine, University of California, San Francisco, San Francisco, California, USA.
Kaiser Permanente · USStanford Medicine · USStanford University · USUniversity of California, San Francisco · US

Funding

Stanford Medicine Center for Longevity and Healthy Aging Research Education CoreP30AG059307 · NIA · STANFORD UNIVERSITY · PI PERIYAKOIL, VYJEYANTHI S, YESAVAGE, JEROME A · 2018 to 2025
$4.9M
Identifying pre-sepsis opportunities for early, targeted intervention - Equipment SupplementR35GM128672 · NIGMS · KAISER FOUNDATION RESEARCH INSTITUTE · PI Vincent Liu · 2018 to 2026
$4.3M
Machine Learning Clinical Order Recommendations for Specialty Consultation CareR56LM013365 · NLM · STANFORD UNIVERSITY · PI CHEN, JONATHAN H. · 2020 to 2020
$394k
NIA NIH HHS P30 AG059307NIA NIH HHS P30AG059307NIGMS NIH HHS R35 GM128672NIH HHS R35GM128672NLM NIH HHS R56 LM013365
6 · The paper itself

Abstract

objectiveTo determine whether novel measures of contextual factors from multi-site electronic health record (EHR) audit log data can explain variation in clinical process outcomes. MATERIALS AND

methodsWe selected one widely-used process outcome: emergency department (ED)-based team time to deliver tissue plasminogen activator (tPA) to patients with acute ischemic stroke (AIS). We evaluated Epic audit log data (that tracks EHR user-interactions) for 3052 AIS patients aged 18+ who received tPA after presenting to an ED at three Northern California health systems (Stanford Health Care, UCSF Health, and Kaiser Permanente Northern California). Our primary outcome was door-to-needle time (DNT) and we assessed bivariate and multivariate relationships with six audit log-derived measures of treatment team busyness and prior team experience.

resultsPrior team experience was consistently associated with shorter DNT; teams with greater prior experience specifically on AIS cases had shorter DNT (minutes) across all sites: (Site 1: -94.73, 95% CI: -129.53 to 59.92; Site 2: -80.93, 95% CI: -130.43 to 31.43; Site 3: -42.95, 95% CI: -62.73 to 23.17). Teams with greater prior experience across all types of cases also had shorter DNT at two sites: (Site 1: -6.96, 95% CI: -14.56 to 0.65; Site 2: -19.16, 95% CI: -36.15 to 2.16; Site 3: -11.07, 95% CI: -17.39 to 4.74). Team busyness was not consistently associated with DNT across study sites.

conclusionsEHR audit log data offers a novel, scalable approach to measure key contextual factors relevant to clinical process outcomes across multiple sites. Audit log-based measures of team experience were associated with better process outcomes for AIS care, suggesting opportunities to study underlying mechanisms and improve care through deliberate training, team-building, and scheduling to maximize team experience.

Indexed as

Ischemic StrokeStrokeBrainFibrinolytic AgentsHumansThrombolytic TherapyTissue Plasminogen ActivatorFibrinolytic AgentsTissue Plasminogen Activatoraudit logbusynessstroketeam experienceteams

Identifiers

PMID36303451
PMCPMC9748597
OpenAlexW4307495489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.