ReviewBioinformatics (Oxford, England)2022
Neuron tracing from light microscopy images: automation, deep learning and bench testing.
Review in Bioinformatics (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Computational Tools for Neuronal Morphometric Analysis: A Systematic Search and Review.Neuroinformatics · 2024Pooled it
- Cerebrovascular Imaging-to-Graph Reconstruction for Individualized Digital Twin Brains.bioRxiv : the preprint server for biology · 2026Article
- A quantitative and precision‑oriented neuronal reconstruction approach based on data grading.Brain informatics · 2026Article
- SegAnyNeuron: a neural image segmentation network with strong generalization performance by modeling image intensity variation.Brain informatics · 2026Article
- Automated Proofreading of Digitally Reconstructed Neural Morphology Enhances Accuracy, Scalability, and Standardization.bioRxiv : the preprint server for biology · 2026Article
- Reconstruction of Axonal Projections of Single Neurons Using PointTree.Bio-protocol · 2026Article
- Widefield Targeted Illumination Microscopy Enables Optically-Sectioned, Motion-Resilient Imaging of Neuronal Fibers and Their Dynamics.Laser & photonics reviews · 2025Article
- Automatic and accurate reconstruction of long-range axonal projections of single-neuron in mouse brain.eLife · 2025Article
- Image enhancement network based on fiber topology-preserving multi-module fusion for neuron reconstruction.Biomedical optics express · 2025Article
- Semi-automated Analysis of Beading in Degenerating Axons.Neuroinformatics · 2025Article
- A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images.Scientific data · 2025Article
- Activity-dependent refinement of axonal projections forms one-to-one connection pattern in the developing chick ciliary ganglion.Frontiers in cellular neuroscience · 2025Article
- Fibre tracing in biomedical images: An objective comparison between seven algorithms.PloS one · 2025Article
- A neuronal imaging dataset for deep learning in the reconstruction of single-neuron axons.Frontiers in neuroinformatics · 2025Article
- Collaborative augmented reconstruction of 3D neuron morphology in mouse and human brains.Nature methods · 2024Article
- Accelerating the continuous community sharing of digital neuromorphology data.FASEB bioAdvances · 2024Article
- Connecto-informatics at the mesoscale: current advances in image processing and analysis for mapping the brain connectivity.Brain informatics · 2024Review
- Quantifying morphologies of developing neuronal cells using deep learning with imperfect annotations.IBRO neuroscience reports · 2024Article
- A modular framework for multi-scale tissue imaging and neuronal segmentation.Nature communications · 2024Article
- From pixels to connections: exploring in vitro neuron reconstruction software for network graph generation.Communications biology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
motivationLarge-scale neuronal morphologies are essential to neuronal typing, connectivity characterization and brain modeling. It is widely accepted that automation is critical to the production of neuronal morphology. Despite previous survey papers about neuron tracing from light microscopy data in the last decade, thanks to the rapid development of the field, there is a need to update recent progress in a review focusing on new methods and remarkable applications.
resultsThis review outlines neuron tracing in various scenarios with the goal to help the community understand and navigate tools and resources. We describe the status, examples and accessibility of automatic neuron tracing. We survey recent advances of the increasingly popular deep-learning enhanced methods. We highlight the semi-automatic methods for single neuron tracing of mammalian whole brains as well as the resulting datasets, each containing thousands of full neuron morphologies. Finally, we exemplify the commonly used datasets and metrics for neuron tracing bench testing.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.