Evidence map›Paper›PMID 36303191›Full record

ArticleAIDS research and therapy2022

PrEP-related stigma and PrEP use among gay, bisexual and other men who have sex with men in Ontario and British Columbia, Canada.

Oscar Javier Pico-Espinosa, Mark Hull, Paul MacPherson, Daniel Grace, Mark Gaspar, Nathan Lachowsky, Saira Mohammed, James Demers, Marshall Kilduff, Robinson Truong and 1 more

Abstract read
In one paragraph

Article in AIDS research and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Oscar Javier Pico-EspinosaSt Michael's Hospital, Toronto, ON, Canada. oscarjavier.picoespinosa@unityhealth.to.
Mark HullBC Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.
Paul MacPhersonUniversity of Ottawa, Ottawa, ON, Canada.
Daniel GraceUniversity of Toronto, Toronto, ON, Canada.
Mark GasparUniversity of Toronto, Toronto, ON, Canada.
Nathan LachowskyUniversity of Victoria, Victoria, BC, Canada.
Saira MohammedBC Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada.
James DemersMAX Ottawa, Ottawa, ON, Canada.
Marshall KilduffAVI Health and Community Services, Victoria, BC, Canada.
Robinson TruongSt Michael's Hospital, Toronto, ON, Canada.
Darrell H S TanSt Michael's Hospital, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to explore the association between PrEP-related stereotypes and perceived disapproval (hereafter PrEP-related stigma), and PrEP use.

methodsWe used data from a cross-sectional online survey among adult gay, bisexual, other men who have sex with men in Ontario and British Columbia, Canada. Participants were recruited 2019-2020 in-person from sexual health clinics and outreach programs, and online through dating mobile applications and websites. We used logistic regression models to explore the relationship between PrEP-related stigma and: 1-being a 'never' versus 'current' PrEP user, and 2-being a 'former' versus 'current' user.

resultsThe median age of the sample was 32 (Q1-Q3 = 27-40), most were white born in Canada (48%), 45% had never used PrEP, 16% were former PrEP users and 39% were current PrEP users. Of 1527 individuals who started the survey, 1190 participants answered questions about PrEP-related stigma: 254 (21.3%) were classified as having low level of PrEP-related stigma, 776 (65.2%) intermediate, and 160 (13.5%) high. No significant association was found when never PrEP users and current PrEP users were compared: adjusted OR = 1.44 (95%-CI: 0.8-2.5). High PrEP-related stigma was positively associated with being a former PrEP user compared to being a current PrEP user: adjusted OR = 2.5 (95%-CI: 1.3-4.9).

conclusionPrEP-related stigma is associated with not using PrEP, particularly with PrEP discontinuation. Our findings indicate that stigma persists as a barrier to PrEP use.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesAdultBritish ColumbiaCross-Sectional StudiesHomosexuality, MaleHumansMaleOntarioSexual BehaviorHealth promotionHealth services accessibilityHIV pre-exposure prophylaxisRetention in careSocial stigma

Identifiers

PMID36303191
PMCPMC9615170

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.