ArticleCellular & molecular immunology2023
Disrupted Ca
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in Cellular & molecular immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Modulation of SERCA1a by Sesquiterpene Lactones: Insights into Inhibition Mechanisms.Cell biochemistry and biophysics · 2026Article
- Peripheral γδ T-cell remodeling in psoriasis is associated with effector-biased transcriptional organization and reduced representation of a circulatingFrontiers in immunology · 2026Article
- TGF-βRII/IL-15 immunotherapeutic complex targets exhausted CD8Journal for immunotherapy of cancer · 2025Article
- Time-series transcriptomic analysis of Nile tilapia reveals the crucial roles of long non-coding RNA and transcription factor in response to Aeromonas veronii infection.BMC genomics · 2025Article
- Explainable deep learning for stratified medicine in inflammatory bowel disease.Genome biology · 2025Article
- Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee.Journal of human immunity · 2025Article
- Impact of static magnetic field exposure onJournal of advanced veterinary and animal research · 2025Article
- Dominant negative variants in ITPR3 impair T cell Ca2+ dynamics causing combined immunodeficiency.The Journal of experimental medicine · 2025Article
- Two cases of combined immunodeficiency with ITPR3 mutations presenting with life-threatening severe EBV-associated hemophagocytic lymphohistiocytosis.Frontiers in immunology · 2025Article
- IP3 receptor depletion in a spontaneous canine model of Charcot-Marie-Tooth disease 1J with amelogenesis imperfecta.PLoS genetics · 2025Article
- ITPR3-associated neuropathy: Report of a further family with adult onset intermediate Charcot-Marie-Tooth disease.European journal of neurology · 2024Article
- A pleiotropic recurrent dominantScience advances · 2024Article
- 10th European Calcium Society symposium: The Ca2+-signaling toolkit in cell function, health and disease.Biology open · 2024Review
- Type 3 IP3 receptor: Its structure, functions, and related disease implications.Channels (Austin, Tex.) · 2023Review
- Understanding IPCell calcium · 2023Review
- Point mutations in the gene encoding IP3 receptor subtype 3 cause impairment in T-cell and B-cell immune responses via dysfunctional CaCellular & molecular immunology · 2023Article
- Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky CaiScience · 2022Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
21 authors at 8 institutions in 3 countries.
Julika Neumann *VIB Center for Brain and Disease Research, Leuven, Belgium.ORCID http://orcid.org/0000-0003-0518-2512
Erika Van Nieuwenhove *VIB Center for Brain and Disease Research, Leuven, Belgium.
Lara E Terry *Department of Pharmacology and Physiology, University of Rochester, Rochester, NY, 14526, USA.ORCID http://orcid.org/0000-0002-0200-4334
Frederik StaelsDepartment of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Taylor R KnebelDepartment of Pharmacology and Physiology, University of Rochester, Rochester, NY, 14526, USA.
Kirsten WelkenhuyzenLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Kankerinstituut, KU Leuven, Leuven, Belgium.
Kourosh AhmadzadehLaboratory of Immunobiology, Department Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.
Mariah R BakerDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0002-1613-9387
Margaux GerbauxDepartment of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Mathijs WillemsenVIB Center for Brain and Disease Research, Leuven, Belgium.
John S BarberVIB Center for Brain and Disease Research, Leuven, Belgium.
Irina I SeryshevaDepartment of Biochemistry and Molecular Biology, Structural Biology Imaging Center, McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0001-6266-3422
Liesbeth De WaeleDepartment of Pediatric Neurology, University Hospitals Leuven, Leuven, Belgium.
François VermeulenDepartment of Pulmonology, University Hospitals Leuven, Leuven, Belgium.
Susan SchlennerDepartment of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Isabelle MeytsUZ Leuven, Leuven, Belgium. isabelle.meyts@uzleuven.be.
David I YuleDepartment of Pharmacology and Physiology, University of Rochester, Rochester, NY, 14526, USA.
Geert BultynckLaboratory of Molecular and Cellular Signaling, Department of Cellular and Molecular Medicine, Leuven Kankerinstituut, KU Leuven, Leuven, Belgium.
Rik SchrijversUZ Leuven, Leuven, Belgium. rik.schrijvers@uzleuven.be.
Stephanie Humblet-BaronDepartment of Microbiology and Immunology, KU Leuven, Leuven, Belgium. stephanie.humbletbaron@kuleuven.be.ORCID http://orcid.org/0000-0003-4684-069X
Adrian ListonVIB Center for Brain and Disease Research, Leuven, Belgium. al989@cam.ac.uk.ORCID http://orcid.org/0000-0002-6272-4085
KU Leuven · BEUniversitair Ziekenhuis Leuven · BEUniversity of Rochester · USVIB-KU Leuven Center for Brain & Disease Research · BEImaging Center · USRega Institute for Medical Research · BEBabraham Institute · GBUniversité Libre de Bruxelles · BE
Funding
[Ca2+]i and Secretory Dynamics in Parotid Acinar CellsR01DE014756 · NIDCR · UNIVERSITY OF ROCHESTER · PI David I Yule · 2002 to 2026
$9.9MTraining Program in Oral ScienceT90DE021985 · NIDCR · UNIVERSITY OF ROCHESTER · PI OVITT, CATHERINE, YULE, DAVID I · 2011 to 2021
$5.6MSUPPORT AND DEVELOPMENT OF EMAN FOR ELECTRON MICROSCOPY IMAGE PROCESSINGR01GM080139 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI LUDTKE, STEVEN J · 2006 to 2022
$5.4MStructure-Function Studies Of IP3R ChannelsR01GM072804 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SERYSHEVA, IRINA I · 2005 to 2023
$4.8MNIDCR NIH HHS R01 DE014756NIDCR NIH HHS T90 DE021985NIGMS NIH HHS R01 GM072804NIGMS NIH HHS R01 GM080139
Abstract
Calcium signaling is essential for lymphocyte activation, with genetic disruptions of store-operated calcium (Ca
Indexed as
CalciumCalcium SignalingInositol 1,4,5-Trisphosphate ReceptorsAnimalsHomeostasisHumansImmune System DiseasesMiceProtein IsoformsCalciumInositol 1,4,5-Trisphosphate ReceptorsITPR3 protein, humanProtein IsoformsCalcium signallingPrimary immunodeficiencyWhole exome sequencing
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.