Evidence map›Paper›PMID 36302927›Full record

ArticleScientific reports2022

On the effectiveness of proton boron fusion therapy (PBFT) at cellular level.

Mehrdad Shahmohammadi Beni, M Rafiqul Islam, Kyeong Min Kim, Dragana Krstic, Dragoslav Nikezic, Kwan Ngok Yu, Hiroshi Watabe

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Microdosimetric Simulation of Gold-Nanoparticle-Enhanced Radiotherapy.International journal of molecular sciences · 2024
    Article
  5. Study of Nuclear Reactions in Therapy of Tumors with Proton Beams.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Mehrdad Shahmohammadi BeniDepartment of Physics, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China.
M Rafiqul IslamGraduate School of Biomedical Engineering, Tohoku University, Sendai, 980-8579, Japan.
Kyeong Min KimKorea Institute of Radiological & Medical Sciences, 75, Nowon-Ro, Nowon-Gu, Seoul, Korea.
Dragana KrsticFaculty of Science, University of Kragujevac, Kragujevac, Serbia.
Dragoslav NikezicFaculty of Science, University of Kragujevac, Kragujevac, Serbia.
Kwan Ngok YuDepartment of Physics, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China. peter.yu@cityu.edu.hk.
Hiroshi WatabeDivision of Radiation Protection and Safety Control, Cyclotron and Radioisotope Center, Tohoku University, 6-3 Aoba, Aramaki, Aoba-Ku, Sendai, Miyagi, 980-8578, Japan. watabe@cyric.tohoku.ac.jp.
Tohoku University · JPUniversity of Kragujevac · RSCity University of Hong Kong · HKKorea Institute of Radiological and Medical Sciences · KR

Funding

Japan Society for the Promotion of Science (JSPS) 20H03615
6 · The paper itself

Abstract

The present work introduced a framework to investigate the effectiveness of proton boron fusion therapy (PBFT) at the cellular level. The framework consisted of a cell array generator program coupled with PHITS Monte Carlo package with a dedicated terminal-based code editor that was developed in this work. The framework enabled users to model large cell arrays with normal, all boron, and random boron filled cytoplasm, to investigate the underlying mechanism of PBFT. It was found that alpha particles and neutrons could be produced in absence of boron mainly because of nuclear reaction induced by proton interaction with

Indexed as

Boron Neutron Capture TherapyProton TherapyBoronMonte Carlo MethodNeutronsProtonsBoronProtons

Identifiers

PMID36302927
PMCPMC9613677
OpenAlexW4307775806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.