Evidence map›Paper›PMID 36302785›Full record

ArticleNPJ science of learning2022

A population-wide gene-environment interaction study on how genes, schools, and residential areas shape achievement.

Rosa Cheesman, Nicolai T Borgen, Torkild H Lyngstad, Espen M Eilertsen, Ziada Ayorech, Fartein A Torvik, Ole A Andreassen, Henrik D Zachrisson, Eivind Ystrom

Abstract read
In one paragraph

Article in NPJ science of learning, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Estimating returns to education using the genetic lottery.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  4. Article
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  6. Article
  7. The genetic lottery goes to school: Better schools compensate for the effects of students' genetic differences.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
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  16. Article
  17. Genetic contributions of noncognitive skills to academic development.bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rosa CheesmanPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway. rosacg@uio.no.ORCID http://orcid.org/0000-0002-6543-0402
Nicolai T BorgenDepartment of Special Needs Education, Faculty of Educational Sciences, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-7638-3293
Torkild H LyngstadDepartment of Sociology & Human Geography, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0001-7830-9305
Espen M EilertsenPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Ziada AyorechPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Fartein A TorvikPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.
Ole A AndreassenNORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-4461-3568
Henrik D ZachrissonDepartment of Special Needs Education, Faculty of Educational Sciences, University of Oslo, Oslo, Norway.
Eivind YstromPROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-4390-6171

Funding

EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)) 818420EC | EC Seventh Framework Programm | FP7 Ideas: European Research Council (FP7-IDEAS-ERC - Specific Programme: "Ideas" Implementing the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities (2007 to 2013)) 818425EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Marie Skłodowska-Curie Actions (H2020 Excellent Science - Marie Skłodowska-Curie Actions) 894675Norges Forskningsråd (Research Council of Norway) 223273Norges Forskningsråd (Research Council of Norway) 273291Norges Forskningsråd (Research Council of Norway) 288083Norges Forskningsråd (Research Council of Norway) 300668
6 · The paper itself

Abstract

A child's environment is thought to be composed of different levels that interact with their individual genetic propensities. However, studies have not tested this theory comprehensively across multiple environmental levels. Here, we quantify the contributions of child, parent, school, neighbourhood, district, and municipality factors to achievement, and investigate interactions between polygenic indices for educational attainment (EA-PGI) and environmental levels. We link population-wide administrative data on children's standardised test results, schools and residential identifiers to the Norwegian Mother, Father, and Child Cohort Study (MoBa), which includes >23,000 genotyped parent-child trios. We test for gene-environment interactions using multilevel models with interactions between EA-PGI and random effects for school and residential environments (thus remaining agnostic to specific features of environments). We use parent EA-PGI to control for gene-environment correlation. We found an interaction between students' EA-PGI and schools suggesting compensation: higher-performing schools can raise overall achievement without leaving children with lower EA-PGI behind. Differences between schools matter more for students with lower EA-PGI, explaining 4 versus 2% of the variance in achievement for students 2 SD below versus 2 SD above the mean EA-PGI. Neighbourhood, district, and municipality variation contribute little to achievement (<2% of the variance collectively), and do not interact with children's individual EA-PGI. Policy to reduce social inequality in achievement in Norway should focus on tackling unequal support across schools for children with difficulties.

Identifiers

PMID36302785
PMCPMC9613652

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.